CAMPSQ986
Title : Dermaseptin-01
GenInfo Identifier : 41016983
Source : Phyllomedusa oreades [Orange-legged leaf frog]
Taxonomy : Animalia, Amphibia
UniProt: P83637
PubMed : 12379643
Activity : Antibacterial, Antiparasitic
Gram Nature : Gram +ve, Gram -ve
Target :
S. aureus ATCC 25923 ( MIC = 3.20 microM), P. aeruginosa ATCC 27853 ( MIC = 6.42 microM), E. coli ATCC 25922 ( MIC = 6.42 microM), A. calcoaceticus wt ( MIC = 25.67 microM), E. coli wt MR ( MIC = 6.42 microM), S. aureus MRSA ( MIC = 12.83 microM), T. cruz ( MIC = 1-4 microM)
Hemolytic Activity :
Human red blood cells (4-128 microg/mL)
Validated : Experimentally validated
Pfam : PF12121 : DD_K ( Dermaseptin )
InterPro : IPR022731 : Dermaseptin.
IPR022731 :
AMP Family : Dermaseptin
Signature :
ID Type Pattern / HMM
DermaseptinH29_3 HMM
DermaseptinH_57 HMM
DermaseptinP29_3 Pattern G-L-W-S-x-I-K-[EQT]-x-G-K-[ES]-[AV]-A-x-A-A-[AG]-K-A-A-[GLV]-x(2)-[AIV]-x-[EGN]-A-[LV]
Gene Ontology :
GO ID Ontology Definition
Evidence
GO:0005576 Cellular component Extracellular region IDA
GO:0050829 Biological process Defense response to Gram-negative bacterium IDA
GO:0050830 Biological process Defense response to Gram-positive bacterium IDA
Length : 29
Sequence:
 GLWSTIKQKGKEAAIAAAKAAGQAALGAL

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