CAMPSQ7547
Title : Interferon-induced guanylate-binding protein 2
Source : Rattus norvegicus [Rat]
Taxonomy : Animalia, Mammals
UniProt: Q63663
Activity : Antiviral
Validated : Predicted
Pfam : PF02263 : GBP ( Guanylate-binding protein, N-terminal domain )
PF02841 : GBP_C ( Guanylate-binding protein, C-terminal domain )
InterPro : IPR030386 :
IPR003191 :
IPR015894 :
IPR027417 :
Gene Ontology :
GO ID Ontology Definition
Evidence
GO:0005737 Cellular component Cytoplasm ISO
GO:0031410 Cellular component Cytoplasmic vesicle ISS
GO:0005794 Cellular component Golgi apparatus ISO
GO:0000139 Cellular component Golgi membrane IEA
GO:0005634 Cellular component Nucleus ISO
GO:0048471 Cellular component Perinuclear region of cytoplasm ISO
GO:0005525 Molecular function GTP binding IBA
GO:0003924 Molecular function GTPase activity IBA
GO:0042802 Molecular function Identical protein binding ISO
GO:0042803 Molecular function Protein homodimerization activity ISO
GO:0044406 Biological process Adhesion of symbiont to host ISO
GO:0035458 Biological process Cellular response to interferon-beta ISO
GO:0071346 Biological process Cellular response to interferon-gamma ISO
GO:0071347 Biological process Cellular response to interleukin-1 ISO
GO:0071222 Biological process Cellular response to lipopolysaccharide ISO
GO:0071356 Biological process Cellular response to tumor necrosis factor ISO
GO:0050830 Biological process Defense response to Gram-positive bacterium ISO
GO:0042832 Biological process Defense response to protozoan ISO
GO:0034504 Biological process Protein localization to nucleus ISO
GO:0009617 Biological process Response to bacterium ISO
Length : 586
Sequence:
 MASEIHMLQPMCLIENTEAHLVINQEALRILSAINQPVVVVAIVGLYRTGKSYLMNKLAG
KRTGFSLGSTVQSHTKGIWMWCVPHPKKAGQTLVLLDTEGLEDVEKGDNQNDCWIFALAV
LLSSTFVYNSMGTINQQAMDQLHYVTELTDLIKSKSSPDQSGIDDSANFVGFFPTFVWAL
RDFSLELEVNGKLVTPDEYLEHSLTLKKGADKKTKSFNEPRLCIRKFFPKRKCFIFDRPA
LRKQLCKLETLGEEELCSEFVEQVAEFTSYIFSYSAVKTLSGGIIVNGPRLKSLVQTYVG
AISSGSLPCMESAVLTLAQIENSAAVQKAITHYEEQMNQKIQMPTETLQELLDLHRLIER
EAIEIFLKNSFKDVDQKFQTELGNLLISKRDAFIKKNSDVSSAHCSDLIEDIFGPLEEEV
KQGTFSKPGGYFLFLQMRQELEKKYNQAPGKGLEAEAVLKKYFESKEDIVETLLKTDQSL
TEAAKEIEVERIKAETAEAANRELAEKQEKFELMMQQKEESYQEHVRQLTEKMKEEQKKL
IEEQDNIIALKLREQEKFLREGYENESKKLLREIENMKRRQSPGKC

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