CAMPSQ7546
Title : Interferon-induced guanylate-binding protein 1
Source : Pongo abelii [Sumatran orangutan]
Taxonomy : Animalia, Mammals
UniProt: Q5RBE1
Activity : Antiviral
Validated : Predicted
Pfam : PF02263 : GBP ( Guanylate-binding protein, N-terminal domain )
PF02841 : GBP_C ( Guanylate-binding protein, C-terminal domain )
InterPro : IPR030386 :
IPR003191 :
IPR015894 :
IPR027417 :
Gene Ontology :
GO ID Ontology Definition
Evidence
GO:0005576 Cellular component Extracellular region IEA
GO:0000139 Cellular component Golgi membrane IEA
GO:0005886 Cellular component Plasma membrane IEA
GO:0005525 Molecular function GTP binding ISS
GO:0003924 Molecular function GTPase activity IEA
GO:0051607 Biological process Defense response to virus IEA
Length : 589
Sequence:
 MASEIHMTGPMCLIESTNGRLMANPEALKILSAITQPMVVVAIVGLYRTGKSYLMNKLAG
KKKGFSLGSTVQSHTKGIWMWCVPHPKKPGHILVLLDTEGLGDVEKGDNQNDSWIFALAV
LLSSTFVYNSIGTINQQAMDQLYYVTELTHRIRSKSSPDENENEVEDSADFVSFFPDFVW
TLRDFSLDLEADGQPLTPDEYLTYSLKLKKGTSQKDETFNLPRLCIRKFFPKKKCFVFDR
PVHRRKLAQLEKLQDEELDPEFVQQVADFCSYIFSNSKTKTLSGGIQVNGPRLESLVLTY
VNAISSGDLPCMENAVLALAQIENSAAVQKAIAHYEQQMGQKVQLPTESLQELLDLHRDS
EREAIEVFIRSSFKDVDHLFQKELAAQLEKKRDDFCKQNQEASSDRCSGLLQVIFSPLEE
EVKAGIYSKPGGYRLFVQKLQDLKKKYYEEPRKGIQAEEILQTYLKSKESMTDAILQTDQ
TLTEKEKEIEVERVKAESAQASAKMLQEMQRKNEQMMEQKERSYQEHLKQLTEKMENDRV
QLLKEQERTLALKLQEQEQLLKEGFQKESRIMKNEIQDLQTKMRRRKAC

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