| CAMPSQ6367 |
| Title : |
Lactotransferrin |
| GenInfo Identifier : |
6136043 |
| Source : |
Bubalus bubalis [Domestic water buffalo] |
| Taxonomy : |
Animalia, Mammals |
| UniProt: |
O77698 |
| Activity : |
Antibacterial |
| Gram Nature : |
Gram -ve |
| Target : |
E.coli, P.aeruginosa |
| Validated : |
Predicted (Based on signature) |
| Pfam : |
PF00405 : Transferrin ( Transferrin )
|
| InterPro : |
IPR030684 :
IPR016357 : Transferrin.
IPR016357 :
IPR001156 : Transferrin_fam.
IPR001156 :
IPR018195 : Transferrin_Fe_BS.
IPR018195 :
|
| AMP Family : |
Transferrin |
| Signature : |
| ID |
Type |
Pattern / HMM |
|
TransferrinP_4 |
Pattern |
W-Q-x(0,1)-R-x(0,1)-M-[KR]-K-[LV] |
|
TransferrinH_4 |
HMM |
 |
|
| Gene Ontology : |
| GO ID |
Ontology |
Definition |
Evidence |
| GO:0005615 |
Cellular component |
Extracellular space |
IEA |
| GO:0042581 |
Cellular component |
Specific granule |
ISS |
| GO:0005506 |
Molecular function |
Iron ion binding |
IEA |
| GO:0004252 |
Molecular function |
Serine-type endopeptidase activity |
IEA |
| GO:0019731 |
Biological process |
Antibacterial humoral response |
ISS |
| GO:0019732 |
Biological process |
Antifungal humoral response |
ISS |
| GO:0060349 |
Biological process |
Bone morphogenesis |
ISS |
| GO:0002227 |
Biological process |
Innate immune response in mucosa |
ISS |
| GO:0006811 |
Biological process |
Ion transport |
IEA |
| GO:0055072 |
Biological process |
Iron ion homeostasis |
IEA |
| GO:0043066 |
Biological process |
Negative regulation of apoptotic process |
ISS |
| GO:0031665 |
Biological process |
Negative regulation of lipopolysaccharide-mediated signaling pathway |
ISS |
| GO:2001205 |
Biological process |
Negative regulation of osteoclast development |
ISS |
| GO:1900229 |
Biological process |
Negative regulation of single-species biofilm formation in or on host organism |
ISS |
| GO:2000308 |
Biological process |
Negative regulation of tumor necrosis factor (ligand) superfamily member 11 production |
ISS |
| GO:0001503 |
Biological process |
Ossification |
IEA |
| GO:1900159 |
Biological process |
Positive regulation of bone mineralization involved in bone maturation |
ISS |
| GO:1902732 |
Biological process |
Positive regulation of chondrocyte proliferation |
ISS |
| GO:0045669 |
Biological process |
Positive regulation of osteoblast differentiation |
ISS |
| GO:0033690 |
Biological process |
Positive regulation of osteoblast proliferation |
ISS |
| GO:0001817 |
Biological process |
Regulation of cytokine production |
ISS |
| GO:0032680 |
Biological process |
Regulation of tumor necrosis factor production |
ISS |
|
| Length : |
708 |
Sequence: |
MKLFVPALLSLGALGLCLAAPRKNVRWCTISQPEWLKCHRWQWRMKKLGAPSITCVRRAF
VLECIRAITEKKADAVTLDGGMVFEAGLDPYKLRPVAAEIYGTKESPQTHYYAVAVVKKG
SNFQLDQLQGRNSCHTGLGRSAGWNIPMGILRPYLSWTESLEPFQGAVAKFFSASCVPCV
DRQAYPNLCQLCKGEGENQCACSPREPYFGYSGAFKCLQDGAGDVAFVKETTVFENLPEK
ADRDQYELLCLNNTRAPVDAFKECHLAQVPSHAVVARSVDGKEDLIWKLLSKAQEKFGKN
KSGSFQLFGSPPGQRDLLFKDCALGFLRIPSKVDSALYLGSRYLTALKNLRETAEEVQAR
RARVVWCAVGPEEQKKCQQWSQQSGQIVTCATASTTDDCIALVLKGEADALSLDGGYIYT
AGKCGLVPVLAENRKSSKHSSLDCVLRPTEGYLAVAVVKKANEGLTWNSLKGKKSCHTAV
DRTAGWNIPMGLIANQTGSCAFDEFFSQSCAPGADPKSRLCALCAGDDQGLDKCVPNSKE
KYYGYTGAFRCLAEDVGDVAFVKNDTVWENTNGESTADWAKNLNREDFRLLCLDGTRKPV
TEAQSCHLAVAPNHAVVSLSERAAHVEQVLLHQQALFGENGKNCPDKFCLFKSETKNLLF
NDNTECLAKLGGRPTYEEYLGTEYVTAIANLKKCSTSPLLEACAFLTR |
