CAMPSQ598
Title : Brevinin-1E
GenInfo Identifier : 728978
Source : Rana esculenta (edible frog ) [Edible frog]
Taxonomy : Animalia, Amphibia
UniProt: P32412 , P84839
PubMed : 8508915
Activity : Antibacterial
Gram Nature : Gram +ve, Gram -ve
Target :
E.coliD21 ( MIC = 1.8 microM), B.megaterium Bm11 ( MIC = 0.4 microM), S.aureus Cowan1 ( MIC = 0.6 microM), P.aeruginosa ATCC15692 ( MIC = 30.6 microM), C. albicans ( MIC = 4.7 microM), S. cerevisiae ( MIC = 3.8 microM)
Hemolytic Activity :
Red blood cells (0.5 microM)
Validated : Experimentally validated
Pfam : PF08018 : Antimicrobial_1 ( Frog antimicrobial peptide )
PF03032 : FSAP_sig_propep ( Brevenin/esculentin/gaegurin/rugosin family )
InterPro : IPR012520 : Antimicrobial_frog_1.
IPR012520 :
IPR004275 : Brevinin.
IPR004275 :
AMP Family : Brevinin
Signature :
ID Type Pattern / HMM
BrevininH24_87 HMM
BrevininH_224 HMM
Gene Ontology :
GO ID Ontology Definition
Evidence
GO:0005576 Cellular component Extracellular region IDA
GO:0050829 Biological process Defense response to Gram-negative bacterium IDA
GO:0050830 Biological process Defense response to Gram-positive bacterium IDA
GO:0044179 Biological process Hemolysis in other organism IDA
GO:0005576 Cellular component Extracellular region IDA
GO:0042742 Biological process Defense response to bacterium IEA
GO:0005576 Biological process Extracellular region IDA
GO:0050829 Biological process Defense response to Gram-negative bacterium IDA
GO:0050830 Biological process Defense response to Gram-positive bacterium IDA
GO:0044179 Biological process Hemolysis in other organism IDA
GO:0005576 Cellular component Extracellular region IDA
GO:0050829 Biological process Defense response to Gram-negative bacterium IDA
GO:0050830 Biological process Defense response to Gram-positive bacterium IDA
GO:0044179 Biological process Hemolysis in another organism IDA
GO:0005576 Cellular component Extracellular region IDA
GO:0042742 Biological process Defense response to bacterium IEA
Length : 24
Sequence:
 FLPLLAGLAANFLPKIFCKITRKC

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