CAMPSQ5779
Title : Brevinin-2HS2A, Brevinin-2HS2B
GenInfo Identifier : 544602101
Source : Odorrana hainanensis [Odor frog]
Taxonomy : Animalia, Amphibia
UniProt: E7EKE0, E7EKE1
PubMed : 22450466
Activity : Antibacterial, Antifungal
Gram Nature : Gram +ve, Gram -ve
Target :
S.aureus ATCC 25923 ( MIC = 19 microM ), B.licheniformis X39 ( MIC = 37.5 microM ), R.rhodochrous X15 ( MIC = 9.5 microM ), P.faecalis X29 ( MIC = 9.5 microM ), C.albicans ATCC 2002 ( MIC = 19 microM ), slime mold 090223 ( MIC = 37.5 microM ), E.faecium 091299 (MIC=150 uM), S.carnosus KHS (MIC=150 uM)
Hemolytic Activity :
Hemolytic activity against human erythrocytes (LC (50)=300 microM).
Validated : Experimentally validated
Comment : Inactive against E.faecalis 981, E.coli, P.aeruginosa ,S.typhi
Pfam : PF08023 : Antimicrobial_2 ( Frog antimicrobial peptide )
PF03032 : FSAP_sig_propep ( Brevenin/esculentin/gaegurin/rugosin family )
InterPro : IPR012521 : Antimicrobial_frog_2.
IPR012521 :
IPR004275 : Brevinin.
IPR004275 :
AMP Family : Brevinin
Signature :
ID Type Pattern / HMM
BrevininH33_60 HMM
BrevininH_224 HMM
Gene Ontology :
GO ID Ontology Definition
Evidence
GO:0005576 Cellular component Extracellular region IEA
GO:0042742 Biological process Defense response to bacterium IEA
GO:0050832 Biological process Defense response to fungus IEA
GO:0044179 Biological process Hemolysis in other organism IEA
GO:0005576 Cellular component Extracellular region IEA
GO:0042742 Biological process Defense response to bacterium IEA
GO:0050832 Biological process Defense response to fungus IEA
GO:0044179 Biological process Hemolysis in other organism IEA
GO:0005576 Biological process Extracellular region IEA
GO:0042742 Biological process Defense response to bacterium IEA
GO:0050832 Biological process Defense response to fungus IEA
GO:0044179 Biological process Hemolysis in other organism IEA
GO:0005576 Biological process Extracellular region IEA
GO:0042742 Biological process Defense response to bacterium IEA
GO:0050832 Biological process Defense response to fungus IEA
GO:0044179 Biological process Hemolysis in other organism IEA
Length : 33
Sequence:
 SLLGTVKDLLIGAGKSAAQSVLKGLSCKLSKDC

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