CAMPSQ3662 |
Title : |
Brevinin-1HN1 |
GenInfo Identifier : |
544602099 |
Source : |
Odorrana hainanensis [Odor frog] |
Taxonomy : |
Animalia, Amphibia |
UniProt: |
E7EKC4 |
PubMed : |
22450466 |
Activity : |
Antibacterial |
Gram Nature : |
Gram +ve |
Target : |
E.faecium 091299 ( MIC = 19 microM), E.faecalis 981 ( MIC = 19 microM ), S.aureus ATCC 25923 ( MIC = 1.2 microM ), S.carnosus KHS ( MIC = 4.8 microM ), B.licheniformis X3 ( MIC = 2.4 microM ), R.rhodochrous X15 ( MIC = 1.2 microM ), P.faecalis X29 ( MIC = 4.8 microM), E. coli ATC 25922 ( MIC = 150 microM ),Slime mould 090223 (IS) ( MIC = 1.2 microM ), C. albicans ATCC2002 ( MIC = 2.4 microM ) |
Hemolytic Activity : |
Hemolytic activity against human erythrocytes (LC50=75 microM) |
Validated : |
Experimentally validated |
Pfam : |
PF08018 : Antimicrobial_1 ( Frog antimicrobial peptide )
PF03032 : FSAP_sig_propep ( Brevenin/esculentin/gaegurin/rugosin family )
|
InterPro : |
IPR012520 : Antimicrobial_frog_1.
IPR012520 :
IPR004275 : Brevinin.
IPR004275 :
|
AMP Family : |
Brevinin |
Signature : |
ID |
Type |
Pattern / HMM |
BrevininH24_87 |
HMM |
 |
BrevininH_224 |
HMM |
 |
|
Gene Ontology : |
GO ID |
Ontology |
Definition |
Evidence |
GO:0005576 |
Cellular component |
Extracellular region |
IEA |
GO:0042742 |
Biological process |
Defense response to bacterium |
IEA |
GO:0050832 |
Biological process |
Defense response to fungus |
IEA |
GO:0044179 |
Biological process |
Hemolysis in other organism |
IEA |
|
Length : |
24 |
Sequence: |
FLPLIASLAANFVPKIFCKITKKC |