CAMPSQ3499
Title : Palustrin-2AJ1
GenInfo Identifier : 374110720
Source : Amolops jingdongensis [Chinese torrent frog]
Taxonomy : Animalia, Amphibia
UniProt: G3ETQ3
PubMed : 21816202
Activity : Antibacterial
Gram Nature : Gram +ve, Gram -ve
Target :
Staphylococcus aureus ATCC25923 ( MIC = 20 microM ), Enterococcus faecalis ATCC29212 ( MIC = 20 microM ), Escherichia coli ATCC25922 ( MIC = 13 microM ), Bacillus pyocyaneus CMCCB1010 ( MIC = 20 microM ), Pseudomonas aeruginosa ATCC27853 ( MIC = 33 microM ), Bacillus dysenteriae ( MIC = 50 microM ), Pseudomonas aeruginosa (IS 350) ( MIC = 50 microM ), Klebsiella pneumonia (IS 59) ( MIC = 50 microM )
Validated : Experimentally validated
Comment : Inactive against Staphylococcus aureus (IS 37#), Escherichia coli (IS 117#), Escherichia coli (IS 218#), Candida albicans ATCC90028, Candida parapsilosis ATCC22019, Staphylococcus aureus (IS 10#), Enterobacter cloacae ATCC13047, Klebsiella pneumonia ATC
Pfam : PF08023 : Antimicrobial_2 ( Frog antimicrobial peptide )
PF03032 : FSAP_sig_propep ( Brevenin/esculentin/gaegurin/rugosin family )
InterPro : IPR012521 : Antimicrobial_frog_2.
IPR012521 :
IPR004275 : Brevinin.
IPR004275 :
AMP Family : Palustrin
Signature :
ID Type Pattern / HMM
PalustrinP29_4 Pattern G-F-[IM]-[DS]-T-[AV]-K-N-[LV]-A-x-N-V-A-[AGV]-T-[LV]-[IL]-D-x-[IL]-[KR]-C-K-[IV]-T-G-G-C
RanateurinH27_5 HMM
Gene Ontology :
GO ID Ontology Definition
Evidence
GO:0005576 Cellular component Extracellular region IDA
GO:0016209 Molecular function Antioxidant activity IEA
GO:0050829 Biological process Defense response to Gram-negative bacterium IDA
GO:0050830 Biological process Defense response to Gram-positive bacterium IDA
GO:0044179 Biological process Hemolysis in other organism IDA
GO:0031640 Biological process Killing of cells of other organism IDA
Length : 29
Sequence:
 GFMDTAKNVAKNVAVTLIDKLRCKVTGGC

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