CAMPSQ3456 |
Title : |
Maximin 28 |
GenInfo Identifier : |
169730572 |
Source : |
Bombina maxima [Giant fire-bellied toad] |
Taxonomy : |
Animalia, Amphibia |
UniProt: |
C3RTJ9 |
PubMed : |
21338048 |
Activity : |
Antibacterial, Antifungal |
Gram Nature : |
Gram +ve, Gram -ve |
Target : |
Candida albicans ATCC 20032 ( MIC = 75 microg/ml ), Staphylococcus aureus ATCC 25923 ( MIC = 4.7 microg/ml ), Escherichia coli ATCC 25922 ( MIC = 9.4 microg/ml ), Bacillus subtilis ATCC 6633 ( MIC = 75 microg/ml ) |
Hemolytic Activity : |
Human erythrocytes ( 27.7 % hemolysis at 125 microg/ml ), Rabiit erythrocytes ( 12.1 % hemolysis at 125 microg/ml ) |
Validated : |
Experimentally validated |
Pfam : |
PF05298 : Bombinin ( Bombinin )
|
InterPro : |
IPR007962 : Bombinin.
IPR007962 :
|
AMP Family : |
Maximin |
Signature : |
ID |
Type |
Pattern / HMM |
MaximinH27_19 |
HMM |
 |
MaximinH_43 |
HMM |
 |
MaximinP27_19 |
Pattern |
I-G-x(2)-[FIL]-[IL]-[GS]-[AGV]-[GLV]-[KR]-x(2)-[FLV]-[KR]-[CG]-[AGL]-x(3)-[FL]-A-x(2)-[FHY]-[ALV] |
|
Gene Ontology : |
GO ID |
Ontology |
Definition |
Evidence |
GO:0005576 |
Cellular component |
Extracellular region |
IEA |
GO:0042742 |
Biological process |
Defense response to bacterium |
IEA |
|
Length : |
27 |
Sequence: |
GIGTKFLGGVKTALKGALKELASTYVN |