CAMPSQ22498
Title : Protegrin 1 [C6,8,13,15Del](5-14), LR10
Source : Synthetic construct
UniProt: P32194
PDB: 2MQ5
Structure Database : CAMPST725
PubMed : 24997421
Activity : Antibacterial
Gram Nature : Gram+, Gram-
Target :
Escherichia coli[MIC = 50 microM], Pseudomonas aeruginosa ATCC 27853[MIC = 200 microM], Klebsiella pneumoniae ATCC 13883[MIC >200 microM], Salmonella enterica subsp. enterica serovar Typhimurium ATCC 14028[MIC = 200 microM], Bacillus subtilis[MIC = 50 microM], Staphylococcus aureus ATCC 25923[MIC = 25 microM], Streptococcus pyogenes ATCC 19615[MIC = 50 microM], Enterococcus faecalis ATCC 29212[MIC = 25 microM]
Validated : Experimentally Validated
InterPro : IPR001894 : Cathelicidin.
IPR018216 : Cathelicidin_CS.
Gene Ontology :
GO ID Ontology Definition
Evidence
GO:0005615 Cellular component Extracellular space IBA
GO:0001530 Molecular function Lipopolysaccharide binding IBA
GO:0061844 Biological process Antimicrobial humoral immune response mediated by antimicrobial peptide IBA
GO:0050829 Biological process Defense response to Gram-negative bacterium IBA
GO:0050830 Biological process Defense response to Gram-positive bacterium IBA
GO:0045087 Biological process Innate immune response IBA
GO:0005615 Cellular component Extracellular space IBA
GO:0001530 Molecular function Lipopolysaccharide binding IBA
GO:0061844 Biological process Antimicrobial humoral immune response mediated by antimicrobial peptide IBA
GO:0050829 Biological process Defense response to Gram-negative bacterium IBA
GO:0050830 Biological process Defense response to Gram-positive bacterium IBA
GO:0045087 Biological process Innate immune response IBA
Length : 10
Sequence:
 LYRRRFVVGR

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