CAMPSQ22498 |
Title : |
Protegrin 1 [C6,8,13,15Del](5-14), LR10 |
Source : |
Synthetic construct |
UniProt: |
P32194 |
PDB: |
2MQ5 |
Structure Database : |
CAMPST725 |
PubMed : |
24997421 |
Activity : |
Antibacterial |
Gram Nature : |
Gram+, Gram- |
Target : |
Escherichia coli[MIC = 50 microM], Pseudomonas aeruginosa ATCC 27853[MIC = 200 microM], Klebsiella pneumoniae ATCC 13883[MIC >200 microM], Salmonella enterica subsp. enterica serovar Typhimurium ATCC 14028[MIC = 200 microM], Bacillus subtilis[MIC = 50 microM], Staphylococcus aureus ATCC 25923[MIC = 25 microM], Streptococcus pyogenes ATCC 19615[MIC = 50 microM], Enterococcus faecalis ATCC 29212[MIC = 25 microM] |
Validated : |
Experimentally Validated |
InterPro : |
IPR001894 : Cathelicidin.
IPR018216 : Cathelicidin_CS.
|
Gene Ontology : |
GO ID |
Ontology |
Definition |
Evidence |
GO:0005615 |
Cellular component |
Extracellular space |
IBA |
GO:0001530 |
Molecular function |
Lipopolysaccharide binding |
IBA |
GO:0061844 |
Biological process |
Antimicrobial humoral immune response mediated by antimicrobial peptide |
IBA |
GO:0050829 |
Biological process |
Defense response to Gram-negative bacterium |
IBA |
GO:0050830 |
Biological process |
Defense response to Gram-positive bacterium |
IBA |
GO:0045087 |
Biological process |
Innate immune response |
IBA |
GO:0005615 |
Cellular component |
Extracellular space |
IBA |
GO:0001530 |
Molecular function |
Lipopolysaccharide binding |
IBA |
GO:0061844 |
Biological process |
Antimicrobial humoral immune response mediated by antimicrobial peptide |
IBA |
GO:0050829 |
Biological process |
Defense response to Gram-negative bacterium |
IBA |
GO:0050830 |
Biological process |
Defense response to Gram-positive bacterium |
IBA |
GO:0045087 |
Biological process |
Innate immune response |
IBA |
|
Length : |
10 |
Sequence: |
LYRRRFVVGR |