| CAMPSQ21405 |
| Title : |
Fowlicidin-2 |
| Source : |
Synthetic construct |
| UniProt: |
Q2IAL7 |
| PDB: |
2GDL |
| Structure Database : |
CAMPST561 |
| PubMed : |
20375584 |
| Activity : |
Antibacterial |
| Gram Nature : |
Gram+, Gram- |
| Target : |
Escherichia coli ATCC 25922[MIC = 2 microM], Salmonella enterica subsp. enterica serovar Enteritidis ATCC 13076[MIC = 1 microM], Klebsiella pneumoniae ATCC 13883[MIC = 2 microM], Listeria monocytogenes ATCC 19115[MIC = 2 microM], Staphylococcus aureus ATCC 25923[MIC = 0.5 microM], Staphylococcus aureus ATCC 25923[MIC = 2 microM], Staphylococcus aureus ATCC BAA-39[MIC = 01-2microM], Staphylococcus aureus ATCC 43300[MIC = 1 microM], Staphylococcus aureus ATCC 43300[MIC = 01-2microM] |
| Hemolytic Activity : |
Human erythrocytes (100% Hemolysis at 200 microM |
| Validated : |
Experimentally Validated |
| InterPro : |
IPR001894 : Cathelicidin.
IPR001894 :
|
| Gene Ontology : |
| GO ID |
Ontology |
Definition |
Evidence |
| GO:0005615 |
Cellular component |
Extracellular space |
IBA |
| GO:0001530 |
Molecular function |
Lipopolysaccharide binding |
IMP |
| GO:0061844 |
Biological process |
Antimicrobial humoral immune response mediated by antimicrobial peptide |
IDA |
| GO:0019835 |
Biological process |
Cytolysis |
IMP |
| GO:0050829 |
Biological process |
Defense response to Gram-negative bacterium |
IDA |
| GO:0050830 |
Biological process |
Defense response to Gram-positive bacterium |
IDA |
| GO:0045087 |
Biological process |
Innate immune response |
IDA |
| GO:0042116 |
Biological process |
Macrophage activation |
IDA |
| GO:0001818 |
Biological process |
Negative regulation of cytokine production |
IDA |
| GO:0005615 |
Cellular component |
Extracellular space |
IBA |
| GO:0001530 |
Molecular function |
Lipopolysaccharide binding |
IMP |
| GO:0061844 |
Biological process |
Antimicrobial humoral immune response mediated by antimicrobial peptide |
IDA |
| GO:0019835 |
Biological process |
Cytolysis |
IMP |
| GO:0050829 |
Biological process |
Defense response to Gram-negative bacterium |
IDA |
| GO:0050830 |
Biological process |
Defense response to Gram-positive bacterium |
IDA |
| GO:0045087 |
Biological process |
Innate immune response |
IDA |
| GO:0042116 |
Biological process |
Macrophage activation |
IDA |
| GO:0001818 |
Biological process |
Negative regulation of cytokine production |
IDA |
|
| Length : |
31 |
Sequence: |
LVQRGRFGRFLRKIRRFRPKVTITIQGSARF |
