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| CAMPSQ20220 | |
| Title : | Defensin-derived D-Peptide A |
| Source : | Synthetic construct |
| PubMed : | 19584534, 15003352, 19154767 |
| Activity : | Antibacterial, Antiparasitic |
| Gram Nature : | Gram+, Gram- |
| Target : | Staphylococcus aureus KO-4[MIC = 600 microg/ml], Pseudomonas aeruginosa[MIC = 400 microg/ml], Trypanosoma brucei brucei GUT Tat3.1[MIC = 205+-22 microM], Staphylococcus aureus ATCC 6538P[MIC = 2 microg/ml], Staphylococcus aureus ATCC 6538P[MIC = 8 microg/ml], Escherichia coli JM109[MIC = 5 microg/ml], Escherichia coli JM109[MIC = 50 microg/ml], Trichophyton mentagrophytes IFO 5466[MIC = 25 microg/ml], Staphylococcus aureus KO-4[MIC = 30 microg/ml], Pseudomonas aeruginosa[MIC = 30 microg/ml], Trypanosoma brucei brucei GUT Tat3.1[MIC = 116+-16 microM], Mouse myeloma P3-X63-Ag8.653[IC50 = 96+-12 microM], Human cervical carcinoma HeLa[IC50 = 167+-18 microM], African green monkey kidney cancer Cos-1[IC50 = 330+-4 microM], Human squamous carcinoma RERF-LC-AI[IC50 = 605+-67 microM], Human glioblastoma U251-MG[IC50 = 589+-11 microM], Human lung cancer VA-13[IC50 >640 microM] |
| Hemolytic Activity : | , Mouse erythrocytes (4% Hemolysis at 640 microM |
| Validated : | Experimentally Validated |
| Comment : | Has anticancer activity |
| Length : | 9 |
Sequence: |
RLYLRIGRR |
| © 2022, Biomedical Informatics Centre, ICMR-NIRRCH | |