CAMPSQ19
Title : Amolopin-1b
GenInfo Identifier : 110348517
Source : Amolops loloensis [rufous-spotted torrent frog]
Taxonomy : Animalia, Amphibia
UniProt: A0SN42
PubMed : 17000029
Activity : Antibacterial, Antifungal
Gram Nature : Gram +ve, Gram -ve
Target :
Staphylococcus aureus ( MIC = 5.50 microg/ml ), Escherichia coli ( MIC = 6.50 microg/ml ), Bacillus dysenteriae ( MIC = 2.20 microg/ml ), Candida albicans ( MIC = 7.50 microg/ml )
Hemolytic Activity :
Hemolytic activity against rabbit RBC(LD50 = 5 microg/ml)
Validated : Experimentally validated
Pfam : PF08018 : Antimicrobial_1 ( Frog antimicrobial peptide )
PF03032 : FSAP_sig_propep ( Brevenin/esculentin/gaegurin/rugosin family )
InterPro : IPR012520 : Antimicrobial_frog_1.
IPR012520 :
IPR004275 : Brevinin.
IPR004275 :
AMP Family : Brevinin
Signature :
ID Type Pattern / HMM
BrevininH24_87 HMM
BrevininH_224 HMM
Gene Ontology :
GO ID Ontology Definition
Evidence
GO:0005576 Cellular component Extracellular region IEA
GO:0042742 Biological process Defense response to bacterium IEA
GO:0050832 Biological process Defense response to fungus IEA
GO:0044179 Biological process Hemolysis in other organism IEA
GO:0045087 Biological process Innate immune response IEA
Length : 24
Sequence:
 FLPLAVSLAANFLPKLFCKITKKC

| © 2022, Biomedical Informatics Centre, ICMR-NIRRCH |
ICMR-National Institute for Research in Reproductive and Child Health, Jehangir Merwanji Street, Parel, Mumbai-400012
Maharashtra, India