CAMPSQ15965
Title : Neutrophil defensin 3
Source : Homo sapiens [Human]
Taxonomy : Animalia
UniProt: P59666
Activity : Antimicrobial
Validated : Predicted
Pfam : PF00323 : Defensin_1 ( Mammalian defensin )
PF00879 : Defensin_propep ( Defensin propeptide )
InterPro : IPR016327 : Alpha-defensin.
IPR016327 :
IPR006080 : Defensin_beta/neutrophil.
IPR006080 :
IPR002366 : Defensin_propep.
IPR002366 :
IPR006081 : Mammalian_defensins.
IPR006081 :
AMP Family : Defensin
Gene Ontology :
GO ID Ontology Definition
Evidence
GO:0035578 Cellular component Azurophil granule lumen TAS
GO:0070062 Cellular component Extracellular exosome HDA
GO:0005576 Cellular component Extracellular region TAS
GO:0005615 Cellular component Extracellular space IDA
GO:0005796 Cellular component Golgi lumen TAS
GO:0042803 Molecular function Protein homodimerization activity IDA
GO:0019731 Biological process Antibacterial humoral response IDA
GO:0061844 Biological process Antimicrobial humoral immune response mediated by antimicrobial peptide IDA
GO:0071222 Biological process Cellular response to lipopolysaccharide IBA
GO:0050832 Biological process Defense response to fungus IEA
GO:0050829 Biological process Defense response to Gram-negative bacterium IBA
GO:0050830 Biological process Defense response to Gram-positive bacterium IDA
GO:0051607 Biological process Defense response to virus IEA
GO:0002227 Biological process Innate immune response in mucosa IDA
GO:0030520 Biological process Intracellular estrogen receptor signaling pathway IDA
GO:0031640 Biological process Killing of cells of other organism IDA
GO:0051673 Biological process Membrane disruption in other organism IBA
GO:0035578 Biological process Azurophil granule lumen TAS
GO:0070062 Biological process Extracellular exosome HDA
GO:0005576 Biological process Extracellular region TAS
GO:0005615 Biological process Extracellular space IDA
GO:0005796 Biological process Golgi lumen TAS
GO:0042803 Biological process Protein homodimerization activity IDA
GO:0019731 Biological process Antibacterial humoral response IDA
GO:0061844 Biological process Antimicrobial humoral immune response mediated by antimicrobial peptide IDA
GO:0071222 Biological process Cellular response to lipopolysaccharide IBA
GO:0050832 Biological process Defense response to fungus IEA
GO:0050829 Biological process Defense response to Gram-negative bacterium IBA
GO:0050830 Biological process Defense response to Gram-positive bacterium IDA
GO:0051607 Biological process Defense response to virus IEA
GO:0002227 Biological process Innate immune response in mucosa IDA
GO:0030520 Biological process Intracellular estrogen receptor signaling pathway IDA
GO:0031640 Biological process Killing of cells of other organism IDA
GO:0051673 Biological process Membrane disruption in other organism IBA
Length : 94
Sequence:
 MRTLAILAAILLVALQAQAEPLQARADEVAAAPEQIAADIPEVVVSLAWDESLAPKHPGS
RKNMDCYCRIPACIAGERRYGTCIYQGRLWAFCC

| © 2022, Biomedical Informatics Centre, ICMR-NIRRCH |
ICMR-National Institute for Research in Reproductive and Child Health, Jehangir Merwanji Street, Parel, Mumbai-400012
Maharashtra, India