CAMPSQ15785
Title : Kininogen-1
Source : Homo sapiens [Human]
Taxonomy : Animalia
UniProt: P01042
Activity : Antimicrobial
Validated : Predicted (Based on signature)
AMP Family : Cystatin
Signature :
ID Type Pattern / HMM
CathelicidinH_140 HMM
Gene Ontology :
GO ID Ontology Definition
Evidence
GO:0072562 Blood microparticle HDA
GO:0062023 Collagen-containing extracellular matrix HDA
GO:0005788 Endoplasmic reticulum lumen TAS
GO:0070062 Extracellular exosome HDA
GO:0005576 Extracellular region HDA
GO:0005615 Extracellular space HDA
GO:0005886 Plasma membrane TAS
GO:0031093 Platelet alpha granule lumen TAS
GO:0004869 Cysteine-type endopeptidase inhibitor activity IDA
GO:0004866 Endopeptidase inhibitor activity IBA
GO:0008201 Heparin binding NAS
GO:0005102 Signaling receptor binding IPI
GO:0008270 Zinc ion binding NAS
GO:0061844 Antimicrobial humoral immune response mediated by antimicrobial peptide IDA
GO:0007596 Blood coagulation IEA
GO:0006954 Inflammatory response IEA
GO:0031640 Killing of cells of other organism IDA
GO:0030195 Negative regulation of blood coagulation IDA
GO:0007162 Negative regulation of cell adhesion IDA
GO:0010951 Negative regulation of endopeptidase activity IBA
GO:0045861 Negative regulation of proteolysis IDA
GO:0043065 Positive regulation of apoptotic process NAS
GO:0007204 Positive regulation of cytosolic calcium ion concentration IDA
GO:0042311 Vasodilation IEA
Length : 644
Sequence:
 MKLITILFLCSRLLLSLTQESQSEEIDCNDKDLFKAVDAALKKYNSQNQSNNQFVLYRIT
EATKTVGSDTFYSFKYEIKEGDCPVQSGKTWQDCEYKDAAKAATGECTATVGKRSSTKFS
VATQTCQITPAEGPVVTAQYDCLGCVHPISTQSPDLEPILRHGIQYFNNNTQHSSLFMLN
EVKRAQRQVVAGLNFRITYSIVQTNCSKENFLFLTPDCKSLWNGDTGECTDNAYIDIQLR
IASFSQNCDIYPGKDFVQPPTKICVGCPRDIPTNSPELEETLTHTITKLNAENNATFYFK
IDNVKKARVQVVAGKKYFIDFVARETTCSKESNEELTESCETKKLGQSLDCNAEVYVVPW
EKKIYPTVNCQPLGMISLMKRPPGFSPFRSSRIGEIKEETTVSPPHTSMAPAQDEERDSG
KEQGHTRRHDWGHEKQRKHNLGHGHKHERDQGHGHQRGHGLGHGHEQQHGLGHGHKFKLD
DDLEHQGGHVLDHGHKHKHGHGHGKHKNKGKKNGKHNGWKTEHLASSSEDSTTPSAQTQE
KTEGPTPIPSLAKPGVTVTFSDFQDSDLIATMMPPISPAPIQSDDDWIPDIQIDPNGLSF
NPISDFPDTTSPKCPGRPWKSVSEINPTTQMKESYYFDLTDGLS

| © 2022, Biomedical Informatics Centre, ICMR-NIRRCH |
ICMR-National Institute for Research in Reproductive and Child Health, Jehangir Merwanji Street, Parel, Mumbai-400012
Maharashtra, India