CAMPSQ15762
Title : Kininogen-1
Source : Mus musculus [Mouse]
Taxonomy : Animalia
UniProt: O08677
Activity : Antimicrobial
Validated : Predicted (Based on signature)
AMP Family : Cystatin
Signature :
ID Type Pattern / HMM
CathelicidinH_140 HMM
Gene Ontology :
GO ID Ontology Definition
Evidence
GO:0062023 Collagen-containing extracellular matrix HDA
GO:0005576 Extracellular region IBA
GO:0005615 Extracellular space ISO
GO:0043231 Intracellular membrane-bounded organelle ISO
GO:0043204 Perikaryon ISO
GO:0004869 Cysteine-type endopeptidase inhibitor activity ISO
GO:0004866 Endopeptidase inhibitor activity IBA
GO:0002020 Protease binding ISO
GO:0005102 Signaling receptor binding ISO
GO:0061844 Antimicrobial humoral immune response mediated by antimicrobial peptide ISO
GO:0007596 Blood coagulation IEA
GO:0006954 Inflammatory response IEA
GO:0031640 Killing of cells of other organism ISO
GO:0030195 Negative regulation of blood coagulation ISO
GO:0007162 Negative regulation of cell adhesion ISO
GO:0010951 Negative regulation of endopeptidase activity IBA
GO:0045861 Negative regulation of proteolysis ISO
GO:0007204 Positive regulation of cytosolic calcium ion concentration ISO
GO:0042311 Vasodilation IEA
Length : 661
Sequence:
 MKLITTLLLCSGLLLTLTQGEEAQEIDCNDEAVFQAVDFSLKQFNPGVKSGNQYMLHRVI
EGTKTDGSPTFYSFKYLIKEGNCSAQSGLAWQDCDFKDAEEAATGECTATVGKRENEFFI
VTQTCKIAPSKAPILKAYFPCIGCVHAISTDSPDLEPVLKHSIEHFNNNTDHSHLFTLRK
VKSAHRQVVAGLNFDITYTIVQTNCSKERFPSLHGDCVALPNGDDGECRGNLFMDINNKI
ANFSQSCTLYSGDDLVEALPKPCPGCPRDIPVDSPELKEVLGHSIAQLNAENDHPFYYKI
DTVKKATSQVVAGTKYVIEFIARETKCSKESNTELAEDCEIKHLGQSLDCNANVYMRPWE
NKVVPTVKCQALDMTEMARRPPGFSPFRSVTVQETKEGRTVSPPYIAREQEERDAETEQG
PTHGHGWLHEKQIKANKNHRGHKHGHDHGHWSPRRHGLGHGHQKPHGLGHGHQLKLDYLR
HQREDGDDHTHTVGHGHGHGHGHGHGHGHGHGHGHGHGHGHGHGKHTNKDKNSVKQTTQR
TESLASSSEYSTTSTQMQGRTEGPTLTPPRAQPTVTSSGFQDSDFIEDVVATTPPYDTGA
HDDLIPDIHVQPDSLSFKLISDFPEATSPKCPGRPWKPASWEDPNTETTEFSDFDLLDAL
S

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