| CAMPSQ140 |
| Title : |
Dermaseptin-B4 |
| GenInfo Identifier : |
13959343 |
| Source : |
Phyllomedusa bicolor [Two-colored leaf frog] |
| Taxonomy : |
Animalia, Amphibia |
| UniProt: |
P81486 |
| PubMed : |
9614066 |
| Activity : |
Antibacterial |
| Gram Nature : |
Gram +ve, Gram -ve |
| Target : |
S. aureus ATCC 25923 ( MIC = 3.0 microM ), P. aeruginosa CIP A22 ( MIC = 4.6 microM ), P. aeruginosa ATCC 27853 ( MIC = 11.6 microM ), E. coli ATCC 25922 ( MIC = 5.0 microM ), E. coli 54127 ( MIC = 2.3 microM ) |
| Validated : |
Experimentally validated |
| Pfam : |
PF12121 : DD_K ( Dermaseptin )
PF03032 : FSAP_sig_propep ( Brevenin/esculentin/gaegurin/rugosin family )
|
| InterPro : |
IPR004275 : Brevinin.
IPR004275 :
IPR022731 : Dermaseptin.
IPR022731 :
IPR020194 : Dermaseptin_anura.
IPR020194 :
|
| AMP Family : |
Dermaseptin |
| Signature : |
| ID |
Type |
Pattern / HMM |
|
DermaseptinH28_12 |
HMM |
 |
|
DermaseptinH_57 |
HMM |
 |
|
DermaseptinP28_12 |
Pattern |
W-x(3,4)-K-x-[IV]-[GL]-x(2)-A-[AG]-x-A-[AV]-[GL]-x(2)-[AV]-x-[DGTV]-x-[ALV]-[GN]-[AEQ] |
|
| Gene Ontology : |
| GO ID |
Ontology |
Definition |
Evidence |
| GO:0005576 |
Cellular component |
Extracellular region |
IEA |
| GO:0042742 |
Biological process |
Defense response to bacterium |
IEA |
| GO:0045087 |
Biological process |
Innate immune response |
IEA |
|
| Length : |
28 |
Sequence: |
ALWKDILKNVGKAAGKAVLNTVTDMVNQ |