CAMPSQ13596
Title : Dermaseptin-TO
Source : Phyllomedusa tomopterna [Tiger-striped leaf frog]
Taxonomy : Animalia, Amphibia
PubMed : 33582221
Activity : Antibacterial, Antifungal
Gram Nature : Gram +ve, Gram -ve
Target :
S. aureus (MIC = 4microM), MRSA (MIC = 64microM), E. faecalis (MIC = 128microM), E.coli (MIC = 8microM), C. albicans (MIC = 32microM)
Hemolytic Activity :
Horse RBC (50% hemolysis at 436.7microM)
Validated : Experimentally validated
Comment : C terminal: NH2, Anticancer activity
AMP Family : Dermaseptin
Signature :
ID Type Pattern / HMM
DermaseptinH28_12 HMM
DermaseptinH_57 HMM
DermaseptinP28_12 Pattern W-x(3,4)-K-x-[IV]-[GL]-x(2)-A-[AG]-x-A-[AV]-[GL]-x(2)-[AV]-x-[DGTV]-x-[ALV]-[GN]-[AEQ]
Length : 28
Sequence:
ALWKDLLKNVGIAAGKAALNKVTDMVNQ

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