CAMPSQ135
Title : Tracheal antimicrobial peptide precursor
GenInfo Identifier : 135310
Source : Bos taurus [Bovine]
Taxonomy : Animalia, Mammals
UniProt: P25068
PubMed : 2023943
Activity : Antibacterial, Antifungal
Gram Nature : Gram +ve, Gram -ve
Target :
E. coli D31 ( MIC = 12-25 microg/ml ), K. pneumoniae 13883 ( MIC = 12-25 microg/ml ), Staphylococcus aureus 25923 ( MIC = 25-50 microg/ml ), Pseudomonas aeruginosa 27853 ( MIC = 25-50 microg/ml ), Candida ablicans ( MIC = 6-12 microg/ml )
Validated : Experimentally validated
Pfam : PF00711 : Defensin_beta ( Beta defensin )
InterPro : IPR001855 : Defensin_beta-typ.
IPR001855 :
IPR006080 : Defensin_beta/neutrophil.
IPR006080 :
AMP Family : Defensin
Signature :
ID Type Pattern / HMM
DefensinH_320 HMM
DefensinH30_10 HMM
Gene Ontology :
GO ID Ontology Definition
Evidence
GO:0005615 Cellular component Extracellular space IBA
GO:0031731 Molecular function CCR6 chemokine receptor binding IBA
GO:0042056 Molecular function Chemoattractant activity IBA
GO:0060326 Biological process Cell chemotaxis IBA
GO:0042742 Biological process Defense response to bacterium IBA
Length : 38
Sequence:
 NPVSCVRNKGICVPIRCPGSMKQIGTCVGRAVKCCRKK

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