| CAMPSQ13349 |
| Title : |
DS4 |
| Source : |
Phyllomedusa hypochondrialis [orange-legged leaf frog] |
| Taxonomy : |
Animalia, Amphibia |
| PubMed : |
33774792 |
| Activity : |
Antibacterial |
| Gram Nature : |
Gram +ve, Gram -ve |
| Target : |
S1 (MIC = 295.97 microg/ml), S2 (MIC = 380.82 microg/ml), S3 (MIC = 343.68 microg/ml), S4 (MIC = 358.13 microg/ml), S5 (MIC = 274.17 microg/ml), S6 (MIC = 330.65 microg/ml), S7 (MIC = 411.06 microg/ml) |
| Hemolytic Activity : |
hRBCs, >50% hemolysis at 8 microg/ml |
| Validated : |
Experimentally validated |
| Comment : |
S1 = E. coli Urine DS, S2 = E. coli Urine MDR, S3 = K. pneumoniae Urine DS, S4 = C. striatum Wound exudate MDR, S5 = C. striatum Wound exudate MDR, S6 = C. striatum Wound exudate MDR, S7 = C. striatum Wound exudate MDR (DS = drug sensitive, MDR = multi drug resistant) |
| AMP Family : |
Dermaseptin |
| Signature : |
| ID |
Type |
Pattern / HMM |
|
DermaseptinH28_12 |
HMM |
 |
|
DermaseptinH_57 |
HMM |
 |
|
DermaseptinP28_12 |
Pattern |
W-x(3,4)-K-x-[IV]-[GL]-x(2)-A-[AG]-x-A-[AV]-[GL]-x(2)-[AV]-x-[DGTV]-x-[ALV]-[GN]-[AEQ] |
|
| Length : |
28 |
Sequence: |
ALWMTLLKKVLKAAAKAALNAVLVGANA |