CAMPSQ12607
Title : Hepcidin pHepc
GenInfo Identifier : 47605566
Source : Sus scrofa [Pig]
Taxonomy : Animalia, Mammals
UniProt: Q8MJ80
PubMed : 28760901
Activity : Antibacterial
Gram Nature : Gram -ve
Target :
E. coli K88
Validated : Experimentally validated
Pfam : PF06446 : Hepcidin ( Hepcidin )
InterPro : IPR010500 : Hepcidin.
IPR010500 :
AMP Family : Hepcidin
Signature :
ID Type Pattern / HMM
HepcidinH25_6 HMM
HepcidinH_22 HMM
HepcidinP25_6 Pattern C-x-[FWY]-C-C-x-C-C-x(4)-C-G-x-C-C-[KR]
Gene Ontology :
GO ID Ontology Definition
Evidence
GO:0005615 Cellular component Extracellular space IBA
GO:0005634 Cellular component Nucleus IEA
GO:0005507 Molecular function Copper ion binding IEA
GO:0005179 Molecular function Hormone activity IEA
GO:0006879 Biological process Cellular iron ion homeostasis IBA
GO:0042742 Biological process Defense response to bacterium IBA
GO:0050832 Biological process Defense response to fungus IEA
GO:0060586 Biological process Multicellular organismal iron ion homeostasis IEA
GO:0002262 Biological process Myeloid cell homeostasis IEA
GO:0045779 Biological process Negative regulation of bone resorption IEA
GO:0050728 Biological process Negative regulation of inflammatory response IEA
GO:1904479 Biological process Negative regulation of intestinal absorption IEA
GO:0034760 Biological process Negative regulation of iron ion transmembrane transport IBA
GO:0000122 Biological process Negative regulation of transcription by RNA polymerase II IEA
GO:1903364 Biological process Positive regulation of cellular protein catabolic process IEA
GO:0043032 Biological process Positive regulation of macrophage activation IEA
GO:0045944 Biological process Positive regulation of transcription by RNA polymerase II IEA
GO:0007259 Biological process Receptor signaling pathway via JAK-STAT IEA
GO:0010039 Biological process Response to iron ion IEA
Length : 25
Sequence:
 DTHFPICIFCCGCCRKAICGMCCKT

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