CAMPSQ12346 |
Title : |
TNS18 |
Source : |
Synthetic construct |
PubMed : |
29767453 |
Activity : |
Antibacterial |
Gram Nature : |
Gram -ve |
Target : |
P. aeruginosa strain PAO1 (MIC = 2microg/ml), P. aeruginosa ZEM-9A (MIC = 8microg/ml), P. aeruginosa ZEM-1A (MIC = 8microg/ml), P. aeruginosa PEJ9.1 (MIC = 16microg/ml), P. aeruginosa PEJ2.6 (MIC = 4microg/ml), A.baumannii ATCC 19606 (MIC = 8microg/ml), E. coli bla OXA-48 (MIC = 16microg/ml), E. coli W3110 (MIC = 8microg/ml), C. freundii bla OXA-48 (MIC = 8microg/ml), E. cloacae bla NDM (MIC = 16microg/ml), K. pneumoniae NCTC 418 (MIC = >64microg/ml), K. pneumoniae bla OXA-48 (MIC = >64microg/ml) |
Hemolytic Activity : |
Human RBCs (MHC = 500 microg/ml) |
Validated : |
Experimentally validated |
Comment : |
K = branching lysine, O = ornithine, B = diaminobutyric acid, K(C10) = side-chain decanoylated lysine. |
Sequence: |
(OF)4(KBL)2KKLK(C10) |