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| CAMPSQ12098 | |
| Title : | OLAP- 11 |
| Source : | Synthetic construct |
| PubMed : | 30066172 |
| Activity : | Antibacterial |
| Gram Nature : | Gram +ve, Gram -ve |
| Target : | S. aureus DM4001 (MIC = 6.25microg/mL, MIC 5% human serum = 6.25microg/mL, MIC 10% human serum = 12.5microg/mL, MIC 4% HSA = 12.5microg/mL, MIC 154mM NaCl = 12.5microg/mL), MRSA DM9808R (MIC = 6.25microg/mL, MIC 5% human serum = 12.5microg/mL, MIC 10% human serum = 6.25microg/mL, MIC 4% HSA = 25microg/mL, MIC 154mM NaCl = 6.25microg/mL), P. aeruginosa DM23155 (MIC = >50microg/mL), K. pneumonia DM4299 (MIC = >50microg/mL), E. coli ATCC25922 (MIC = 50microg/mL) |
| Hemolytic Activity : | Rabbit red blood cells (HC50 = >1000 microg/mL) |
| Validated : | Experimentally validated |
| Comment : | Cn represents the number of carbon units present in the lipid; R, arginine; K, lysine. The second lysine from the C-terminus is a branching unit |
Sequence: |
(C8R-C8RC8RC8R)2KK |
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