CAMPSQ11243 |
Title : |
R2PLx |
Source : |
Rana palustris [Pickerel frog] |
Taxonomy : |
Animalia, Amphibia |
PubMed : |
30279210 |
Activity : |
Antibacterial, Antifungal, Anticancer |
Gram Nature : |
Gram +ve, Gram -ve |
Target : |
S. aureus (NCTC 10788) (MIC = 32microM), E. coli (NCTC 10418) (MIC = 32microM), C. albicans (NCTC 1467) (MIC = 256microM), MRSA (ATCC 12493) (MIC = 256microM), E. fecalis (NCTC 12697) (MIC = 128microM), P. aeruginosa (ATCC 27853) (MIC = >512microM), Prostate cancer cell, PC-3 |
Hemolytic Activity : |
Horse RBC (>10 hemolysis at 512microM) |
Validated : |
Experimentally validated |
Comment : |
Antiproliferative activity against cancer cells |
AMP Family : |
Palustrin |
Signature : |
ID |
Type |
Pattern / HMM |
PalustrinP28_3 |
Pattern |
I-[LM]-[DR]-[GT]-[LV]-K-x-[AL]-[AG]-x(2)-[GL]-[AQ]-[AG]-x-[LV]-x-[CD]-[EK]-[IL]-x(2)-K |
|
Length : |
28 |
Sequence: |
GIMDTVKNAAKNLAGQLLDKLKCKITAC |