CAMPSQ10688
Title : Temporin-SHf
Source : Pelophylax saharicus [Sahara frog]
Taxonomy : Animalia
UniProt: D4YWD1
PubMed : 20308076
Activity : Antibacterial, Antifungal
Gram Nature : Gram +ve, Gram -ve
Target :
E.coli ATCC 25922 (MIC = 25 microM), E.coli ATCC 35218 (MC > 200 microM), Escherichia coli D21 (MIC = 100 microM), E.coli ML-35p (MIC = 30 microM), P.aeruginosa ATCC 27853 (MIC > 200 microM), Staphylococcus aureus ATCC 25923 (MIC=12.5 microM), E.faecalis ATCC 29212 (MIC=50 microM), B.megaterium (MIC = 3 microM), C.albicans ATCC 90028 (MIC= 50 microM), C.parapsilosis ATCC 22019 (MIC = 50 microM), S.cerevisiae (MIC = 12.5 microM), A.flavus (MIC >200 microM)
Hemolytic Activity :
Human RBCs (LC50 = 200 microM)
Validated : Experimentally validated
Comment : Inactive against L. infantumpromastigotes, L. infantumamastigotes; C terminal: NH2
Pfam : PF03032 : FSAP_sig_propep ( Brevenin/esculentin/gaegurin/rugosin family )
InterPro : IPR004275 : Brevinin.
IPR004275 :
AMP Family : Temporin
Gene Ontology :
GO ID Ontology Definition
Evidence
GO:0005576 Cellular component Extracellular region IEA
GO:0016020 Cellular component Membrane IEA
GO:0042742 Biological process Defense response to bacterium IEA
GO:0044179 Biological process Hemolysis in other organism IEA
GO:0045087 Biological process Innate immune response IEA
GO:0005576 Cellular component Extracellular region IEA
GO:0016020 Cellular component Membrane IEA
GO:0044218 Cellular component Other organism cell membrane IEA
GO:0042742 Biological process Defense response to bacterium IEA
GO:0044179 Biological process Hemolysis in another organism IEA
GO:0045087 Biological process Innate immune response IEA
Length : 8
Sequence:
 FFFLSRIF

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