The ranacyclin family comprises of short antimicrobial peptides initially isolated from the frog Rana esculenta. Structurally they adopt a random-coil composition and form transmembrane pores in the membrane. They show potent antimicrobial and antifungal properties [PMID: 14636071].
Patterns
RanacyclinP17_3
A-x-R-G-C-W-T-K-[NS]-Y-[PS]-P-K-P-C
RanacyclinP19_4
L-[SV]-G-C-x-T-K-S-[FWY]-P-x-K-P-C-[FL]-x-[NR]
RanacyclinP20_5
A-L-x-G-C-W-T-K-S-x-P-P-x-P-C-x-G-[KR]
RanacyclinP_13
G-C-x-T-K-[NS]-x-[PS]-x(2)-P-C
HMMs
RanacyclinH17_3
RanacyclinH19_4
RanacyclinH20_5
RanacyclinH_13
Note:
The format for Signature ID is the family name, followed by H or P for HMM or Pattern respectively. The integer suffixed to H or P denotes the length of the sequences used to create the family signature. If no integer is suffixed, it indicates that the signature was created using all the sequences of the family. The integer following the underscore denotes the number of sequences used for the creation of signatures.
For example:
AureinH_21 is a HMM for Aurein family created using 21 sequences.
AureinP16_9 is a pattern for Aurein family derived using 9 input sequences that are 16 residues long.
