Description |
Members of this protein family are precursors of TOMMs, that is, thizazole/oxazole-modified microcins. Members are about 42 residues in length, have a C-terminal region of extremely low complexity rich in Ser, and are often missed by ab initio gene callers. In the dimethylated form plantazolicin A, Bacillus amyloliquefaciens plantazolicin has the antibiotic activity of inhibiting growth of Gram-positive bacteria. The desmethyl form, plantazolicin B, has no antibiotic activity. The mode of action appears to be disruption of cell walls and lysis of cells. [PMID: 20971906, PMID: 21950656]. |
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Note:
The format for Signature ID is the family name, followed by H or P for HMM or Pattern respectively. The integer suffixed to H or P denotes the length of the sequences used to create the family signature. If no integer is suffixed, it indicates that the signature was created using all the sequences of the family. The integer following the underscore denotes the number of sequences used for the creation of signatures.
For example:
AureinH_21 is a HMM for Aurein family created using 21 sequences.
AureinP16_9 is a pattern for Aurein family derived using 9 input sequences that are 16 residues long. |
