Nigrocins are isolated from Korean frog Rana nigromaculata. These are lysine rich peptides containing two conserved cysteine residues at the C-terminal region (rana box). Nigrocins are active against gram positive and gram negative bacteria and fungi. They show no haemolytic activity against human RBS probably due to the interspersed distribution of polar residues among the hydrophobic residues interrupting the hydrophobicity of peptides [PMID: 11682065].
HMMs
NigrocinH21_35
NigrocinH_39
Note:
The format for Signature ID is the family name, followed by H or P for HMM or Pattern respectively. The integer suffixed to H or P denotes the length of the sequences used to create the family signature. If no integer is suffixed, it indicates that the signature was created using all the sequences of the family. The integer following the underscore denotes the number of sequences used for the creation of signatures.
For example:
AureinH_21 is a HMM for Aurein family created using 21 sequences.
AureinP16_9 is a pattern for Aurein family derived using 9 input sequences that are 16 residues long.
