This family consists of several caerin 1 proteins from Litoria species, Australian tree frogs. The caerin 1 peptides are among the most powerful of the broad-spectrum antibiotic amphibian peptides [PMID: 12717721]. These peptides are excreted from amphibian skin, and can interact with and disrupt bacterial membranes, leading to the permeabilisation of the cell membrane.
Note:
The format for Signature ID is the family name, followed by H or P for HMM or Pattern respectively. The integer suffixed to H or P denotes the length of the sequences used to create the family signature. If no integer is suffixed, it indicates that the signature was created using all the sequences of the family. The integer following the underscore denotes the number of sequences used for the creation of signatures.
For example:
AureinH_21 is a HMM for Aurein family created using 21 sequences.
AureinP16_9 is a pattern for Aurein family derived using 9 input sequences that are 16 residues long.
