CAMPSQ877
Title : Cathelin-related peptide SC5
GenInfo Identifier : 1710861
Source : Ovis aries [Sheep]
Taxonomy : Animalia, Mammals
UniProt: P49928 , P49929
PDB: 1FRY
Structure Database : CAMPST23
PubMed : 8549789
Activity : Antibacterial, Antifungal
Gram Nature : Gram +ve, Gram -ve
Target :
Staphylococcus aureus 25923 ( MIC = 5 - 10 microg/ml) , Pseudomonas aeruginosa 27853 ( MIC = 5 - 10 microg/ml), Klebsiella pneumoniae 13883 ( MIC = 2.5-5 microg/ml) , Candida albicans 14053 ( MIC = 10-25 microg/ml), Refer pmid-10768969[ Pseudomonas aeruginosa PAO1 ( MIC = 0.17 microM ), Pseudomonas aeruginosa MR3007 ( MIC = 0.34 microM ), Escherichia coli DH5a ( MIC = 0.10 microM ) , Escherichia coli ML-35p ( MIC = 0.18 microM ) Staphylococcus aureus 930918-3 ( MIC = 0.31 microM ), MRSA ATCC 33591 ( MIC = 1.24 microM )]
Validated : Experimentally validated
InterPro : IPR001894 : Cathelicidin.
IPR018216 : Cathelicidin_CS.
AMP Family : Cathelicidin
Signature :
ID Type Pattern / HMM
CathelicidinH29_5 HMM
CathelicidinH_140 HMM
Gene Ontology :
GO ID Ontology Definition
Evidence
GO:0005576 Cellular component Extracellular region IEA
GO:0019835 Biological process Cytolysis IMP
GO:0050829 Biological process Defense response to Gram-negative bacterium IMP
GO:0050830 Biological process Defense response to Gram-positive bacterium IMP
GO:0005576 Cellular component Extracellular region IEA
GO:0008219 Biological process Cell death IMP
GO:0019835 Biological process Cytolysis IMP
GO:0050829 Biological process Defense response to Gram-negative bacterium IMP
GO:0050830 Biological process Defense response to Gram-positive bacterium IMP
GO:0005576 Biological process Extracellular region IEA
GO:0019835 Biological process Cytolysis IMP
GO:0050829 Biological process Defense response to Gram-negative bacterium IMP
GO:0050830 Biological process Defense response to Gram-positive bacterium IMP
GO:0005576 Biological process Extracellular region IEA
GO:0008219 Biological process Cell death IMP
GO:0019835 Biological process Cytolysis IMP
GO:0050829 Biological process Defense response to Gram-negative bacterium IMP
GO:0050830 Biological process Defense response to Gram-positive bacterium IMP
GO:0005576 Cellular component Extracellular region IEA
GO:0019835 Biological process Cytolysis IMP
GO:0050829 Biological process Defense response to Gram-negative bacterium IMP
GO:0050830 Biological process Defense response to Gram-positive bacterium IMP
GO:0005576 Cellular component Extracellular region IEA
GO:0008219 Biological process Cell death IMP
GO:0019835 Biological process Cytolysis IMP
GO:0050829 Biological process Defense response to Gram-negative bacterium IMP
GO:0050830 Biological process Defense response to Gram-positive bacterium IMP
Length : 29
Sequence:
 RGLRRLGRKIAHGVKKYGPTVLRIIRIAG

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