CAMPSQ858
Title : Protegrin-1
GenInfo Identifier : 1730503
Source : Sus scrofa [pig]
Taxonomy : Animalia, Mammals
UniProt: P32194
PDB: 1PG1, 1ZY6
Structure Database : CAMPST59, CAMPST105
PubMed : 8647100
Activity : Antibacterial
Gram Nature : Gram +ve, Gram -ve
Target :
E. coli ( MIC = 64 microg/ml) , S. aureus ( MIC = 64 microg/ml) , S. epiderrnidis ( MIC = 2 microg/ml)
Validated : Experimentally validated
InterPro : IPR001894 : Cathelicidin.
IPR018216 : Cathelicidin_CS.
AMP Family : Cathelicidin
Signature :
ID Type Pattern / HMM
CathelicidinH18_7 HMM
CathelicidinH_140 HMM
Gene Ontology :
GO ID Ontology Definition
Evidence
GO:0005615 Cellular component Extracellular space IBA
GO:0001530 Molecular function Lipopolysaccharide binding IBA
GO:0061844 Biological process Antimicrobial humoral immune response mediated by antimicrobial peptide IBA
GO:0050829 Biological process Defense response to Gram-negative bacterium IBA
GO:0050830 Biological process Defense response to Gram-positive bacterium IBA
GO:0045087 Biological process Innate immune response IBA
GO:0005615 Cellular component Extracellular space IBA
GO:0001530 Molecular function Lipopolysaccharide binding IBA
GO:0061844 Biological process Antimicrobial humoral immune response mediated by antimicrobial peptide IBA
GO:0050829 Biological process Defense response to Gram-negative bacterium IBA
GO:0050830 Biological process Defense response to Gram-positive bacterium IBA
GO:0045087 Biological process Innate immune response IBA
Length : 18
Sequence:
 RGGRLCYCRRRFCVCVGR

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