CAMPSQ848
Title : Defensin
GenInfo Identifier : 61252268
Source : Phlebotomus duboscqi [Sandfly]
Taxonomy : Animalia, Insects
UniProt: P83404
PubMed : 15557638
Activity : Antibacterial, Antifungal
Gram Nature : Gram +ve
Target :
S. aureus ( MIC = 0.78-1.56 microM) , Aspergillus fumigatus ( MIC = 12.5-25 microM) , F. culmorum ( MIC = 1.56-3.12 microM) , F. oxysporum ( MIC = 3.12-6.25 microM), Neurospora crassa ( MIC = 6.25-12.5 microM) , T. viride ( MIC = 3.12-6.25 microM) , Trichophyton mentagrophytes ( MIC = 25-50 microM), Candida albicans ( MIC = 6.25-12.5 microM) , S. cerevisiae ( MIC = 25-50 microM) , L. major promastigote forms ( IC50 = 68-85 microM)
Validated : Experimentally validated
Pfam : PF01097 : Defensin_2 ( Arthropod defensin )
InterPro : IPR001542 : Defensin_invertebrate/fungal.
IPR003614 : Scorpion_toxin-like.
AMP Family : Defensin
Gene Ontology :
GO ID Ontology Definition
Evidence
GO:0005576 Cellular component Extracellular region IDA
GO:0050832 Biological process Defense response to fungus IDA
GO:0050830 Biological process Defense response to Gram-positive bacterium IDA
GO:0045087 Biological process Innate immune response IEA
GO:0031640 Biological process Killing of cells of other organism IEA
Length : 40
Sequence:
 ATCDLLSAFGVGHAACAAHCIGHGYRGGYCNSKAVCTCRR

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