CAMPSQ789 |
Title : |
HmdSL-37, Antibacterial protein LL-37 |
GenInfo Identifier : |
115503705 |
Source : |
Hylobates moloch [Gibbon] |
Taxonomy : |
Animalia, Mammals |
UniProt: |
Q1KLX8 |
PubMed : |
16720578 |
Activity : |
Antibacterial, Antifungal |
Gram Nature : |
Gram +ve, Gram -ve |
Target : |
In 20% TSB in SPB medium E. coli ( MIC = 2 microM ) , P. aeruginosa ( MIC = 8 microM ) , S. aureus ( MIC > 32 microM ) , E. faecalis ( MIC = 8 microM) . In 20% SAB in SPB C. albicans ( MIC >32 microM ). |
Validated : |
Experimentally validated |
Pfam : |
PF12153 : CAP18_C ( LPS binding domain of CAP18 (C terminal) )
|
InterPro : |
IPR001894 : Cathelicidin.
IPR018216 : Cathelicidin_CS.
IPR022746 : Cathlecidin_C.
|
AMP Family : |
Cathelicidin |
Signature : |
ID |
Type |
Pattern / HMM |
CathelicidinH37_9 |
HMM |
|
CathelicidinH_140 |
HMM |
|
|
Gene Ontology : |
GO ID |
Ontology |
Definition |
Evidence |
GO:0005576 |
Cellular component |
Extracellular region |
IEA |
GO:0042742 |
Biological process |
Defense response to bacterium |
IEA |
GO:0042119 |
Biological process |
Neutrophil activation |
ISS |
|
Length : |
37 |
Sequence: |
SLGNFFRKARKKIGEEFKRIVQRIKDFLQHLIPRTEA |