CAMPSQ736
Title : Decoralin
GenInfo Identifier : 193805999
Source : Oreumenes decoratus [Potter wasp]
Taxonomy : Animalia, Insects
UniProt: P85870
PubMed : 17981364, 28105725, 28795464
Activity : Antibacterial, Antifungal
Gram Nature : Gram +ve, Gram -ve
Target :
S.aureus CCT 6538 ( MIC = 40 microM) , S.saprophyticus ( MIC = 40 microM) , B.subtilis CCT 2471 ( MIC = 40 microM) , B.thuringiensis ( MIC = 40 microM) , E.coli ATCC 25922 ( MIC = 80 microM) , E.coli CCT 1371 ( MIC = 160 microM ) , K.pneumonia ATCC 13883 ( MIC = 80 microM) , A.faecalis ATCC 8750 ( MIC = 40 microM ) , C.albicans ( MIC = 40 microM ) , L.major promastigotes ( IC50 = 72 microM ); [Refer PubMed ID - 28105725 (C-terminal: NH2):Candida albicans(MIC=6.25microM)]; [Refer PubMed ID - 28795464: Micrococcus luteus A 270 (MIC = 0.8microM/L), Escherichia coli SBS 363 (MIC = 1.6microM/L), Salmonella arizonae ATCC 13314 (MIC = 25microM/L), Bacillus subtilis ATCC 6633 (MIC = 6.2microM/L), Pseudomonas aeruginosa ATCC 27853 (MIC = 1.6microM/L), Candida albicans MDM8 (MIC = 0.8microM/L)]
Hemolytic Activity :
Weak hemolytic activity towards human , mouse erythrocytes, [Refer PubMed ID - 28795464: Human RBCS (Maximum nonhemolytic concentration = 1.6microM/L)]
Validated : Experimentally validated
Gene Ontology :
GO ID Ontology Definition
Evidence
GO:0005576 Cellular component Extracellular region IDA
GO:0016020 Cellular component Membrane IEA
GO:0019835 Biological process Cytolysis IEA
GO:0050832 Biological process Defense response to fungus IDA
GO:0050829 Biological process Defense response to Gram-negative bacterium IDA
GO:0050830 Biological process Defense response to Gram-positive bacterium IDA
GO:0042832 Biological process Defense response to protozoan IDA
GO:0031640 Biological process Killing of cells of other organism IEA
GO:0043303 Biological process Mast cell degranulation IEA
GO:0043306 Biological process Positive regulation of mast cell degranulation IDA
GO:0005576 Cellular component Extracellular region IDA
GO:0016020 Cellular component Membrane IEA
GO:0044218 Cellular component Other organism cell membrane IEA
GO:0019835 Biological process Cytolysis IEA
GO:0050832 Biological process Defense response to fungus IDA
GO:0050829 Biological process Defense response to Gram-negative bacterium IDA
GO:0050830 Biological process Defense response to Gram-positive bacterium IDA
GO:0042832 Biological process Defense response to protozoan IDA
GO:0031640 Biological process Killing of cells of another organism IEA
GO:0043303 Biological process Mast cell degranulation IEA
GO:0043306 Biological process Positive regulation of mast cell degranulation IDA
Length : 11
Sequence:
 SLLSLIRKLIT

| © 2022, Biomedical Informatics Centre, ICMR-NIRRCH |
ICMR-National Institute for Research in Reproductive and Child Health, Jehangir Merwanji Street, Parel, Mumbai-400012
Maharashtra, India