CAMPSQ729 |
Title : |
Heliomicin |
GenInfo Identifier : |
159162451 |
Source : |
Heliothis virescens [Tobacco budworm moth] |
Taxonomy : |
Animalia, Insects |
UniProt: |
P81544 |
PDB: |
1I2U, 1I2V |
Structure Database : |
CAMPST339, CAMPST29 |
PubMed : |
10092609 |
Activity : |
Antifungal |
Target : |
N. crassa ( MIC = 0.1-0.2 microM) , F. culmorum ( MIC = 0.2-0.4 microM) , F. oxysporum ( MIC = 1.5-3 microM) , N. haematococca ( MIC = 0.4-0.8 microM) , A. fumigatus ( MIC = 6-12 microM) , T. viride ( MIC = 1.5-3 microM) , C. albicans ( MIC = 2.5-5 microM) , C. neoformans ( MIC = 2.5-5 microM ) |
Validated : |
Experimentally validated |
Comment : |
Inactive against E. coli 363 (50 microM) , M. luteus (50 microM) , C. glabrata (50 microM) , S. cerevisiae (50 microM) |
InterPro : |
IPR001542 : Defensin_invertebrate/fungal.
IPR003614 : Scorpion_toxin-like.
IPR002061 : Scorpion_toxinL/defesin.
|
AMP Family : |
Defensin |
Gene Ontology : |
GO ID |
Ontology |
Definition |
Evidence |
GO:0005576 |
Cellular component |
Extracellular region |
IEA |
GO:0050832 |
Biological process |
Defense response to fungus |
IEA |
GO:0045087 |
Biological process |
Innate immune response |
IEA |
GO:0031640 |
Biological process |
Killing of cells of other organism |
IEA |
|
Length : |
44 |
Sequence: |
DKLIGSCVWGAVNYTSDCNGECKRRGYKGGHCGSFANVNCWCET |