CAMPSQ728
Title : Human beta defensin 2
GenInfo Identifier : 3818537
Source : Homo sapiens [Human]
Taxonomy : Animalia, Mammals
UniProt: O15263
PDB: 1E4Q, 1FD3, 1FD4, 1FQQ
Structure Database : CAMPST498, CAMPST20, CAMPST21, CAMPST508
PubMed : 10603376
Activity : Antibacterial
Gram Nature : Gram -ve
Target :
E.coli D31 ( MIC = 62 microg/ml )
Validated : Experimentally validated
Pfam : PF00711 : Defensin_beta ( Beta defensin )
InterPro : IPR001855 : Defensin_beta-typ.
IPR006080 : Defensin_beta/neutrophil.
AMP Family : Defensin
Gene Ontology :
GO ID Ontology Definition
Evidence
GO:0005576 Cellular component Extracellular region TAS
GO:0005615 Cellular component Extracellular space IDA
GO:0005796 Cellular component Golgi lumen TAS
GO:0031731 Molecular function CCR6 chemokine receptor binding IDA
GO:0042056 Molecular function Chemoattractant activity IBA
GO:0061844 Biological process Antimicrobial humoral immune response mediated by antimicrobial peptide IDA
GO:0060326 Biological process Cell chemotaxis IBA
GO:0006935 Biological process Chemotaxis IDA
GO:0042742 Biological process Defense response to bacterium IMP
GO:0050829 Biological process Defense response to Gram-negative bacterium IDA
GO:0050830 Biological process Defense response to Gram-positive bacterium IDA
GO:0007186 Biological process G protein-coupled receptor signaling pathway TAS
GO:0006955 Biological process Immune response TAS
GO:0031640 Biological process Killing of cells of other organism IDA
GO:0005576 Cellular component Extracellular region TAS
GO:0005615 Cellular component Extracellular space IDA
GO:0005796 Cellular component Golgi lumen TAS
GO:0031731 Molecular function CCR6 chemokine receptor binding IDA
GO:0042056 Molecular function Chemoattractant activity IBA
GO:0005546 Molecular function Phosphatidylinositol-4,5-bisphosphate binding IDA
GO:0061760 Biological process Antifungal innate immune response IDA
GO:0061844 Biological process Antimicrobial humoral immune response mediated by antimicrobial peptide IDA
GO:0060326 Biological process Cell chemotaxis IBA
GO:0006935 Biological process Chemotaxis IDA
GO:0042742 Biological process Defense response to bacterium IMP
GO:0050832 Biological process Defense response to fungus IDA
GO:0050829 Biological process Defense response to Gram-negative bacterium IDA
GO:0050830 Biological process Defense response to Gram-positive bacterium IDA
GO:0007186 Biological process G protein-coupled receptor signaling pathway TAS
GO:0006955 Biological process Immune response TAS
GO:0031640 Biological process Killing of cells of another organism IDA
GO:0051673 Biological process Membrane disruption in another organism IDA
Length : 39
Sequence:
 DPVTCLKSGAICHPVFCPRRYKQIGTCGLPGTKCCKKPP

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