CAMPSQ48
Title : Latarcin-5
GenInfo Identifier : 115311727
Source : Lachesana tarabaevi [Spider]
Taxonomy : Animalia, Arachnida
UniProt: Q1ELU9
PubMed : 16735513, 19563807
Activity : Antibacterial, Antifungal
Gram Nature : Gram +ve, Gram -ve
Target :
A. globiformis VKM Ac-1112 ( MIC = 1.1 microM), B. subtilis VKM B-501 ( MIC = 0.6 microM), E. coli DH5-alpha ( MIC = 0.6 microM), E. coli MH1 ( MIC = 0.6 microM), P. aeruginosa PAO1 ( MIC = 18 microM) , P. pastoris GS115 ( MIC = >37 microM), S. cerevisiae Y190 ( MIC = >37 microM), [Refer PubMed ID-19563807: E. coli ( MIC = 0.7 microM ), B. subtilis ( MIC = 0.7 microM ), S. aureus ( MIC = 0.7 microM )]
Hemolytic Activity :
Human erythrocytes (EC50 = 12microM)
Validated : Experimentally validated
Comment : Refer PubMed ID - 19563807: C terminal: NH2
Pfam : PF10279 : Latarcin ( Latarcin precursor )
InterPro : IPR018802 : Latarcin_precursor.
IPR018802 :
AMP Family : Latarcin
Signature :
ID Type Pattern / HMM
LatarcinH_13 HMM
Gene Ontology :
GO ID Ontology Definition
Evidence
GO:0005576 Cellular component Extracellular region IEA
GO:0090729 Molecular function Toxin activity IEA
GO:0042742 Biological process Defense response to bacterium IEA
GO:0050832 Biological process Defense response to fungus IEA
GO:0044179 Biological process Hemolysis in other organism IEA
Length : 28
Sequence:
 GFFGKMKEYFKKFGASFKRRFANLKKRL

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