CAMPSQ459 |
Title : |
Esculentin-1 |
GenInfo Identifier : |
416969 |
Source : |
Rana esculenta [Edible frog] |
Taxonomy : |
Animalia, Amphibia |
UniProt: |
P32414 |
PubMed : |
8508915 |
Activity : |
Antibacterial, Antifungal |
Gram Nature : |
Gram +ve, Gram -ve |
Target : |
E.coliD21 ( MIC = 0.2 microM), B. megaterrum Bm11 ( MIC = 0.1 microM), S.aureus Cowan1 ( MIC = 0.4 microM), P.aeruginosaATCC15692 ( MIC = 0.7 microM), C.albicans ( MIC = 0.5 microM), S. cerevisiae ( MIC = 0.9 microM) |
Hemolytic Activity : |
Red blood cells (>100 microM) |
Validated : |
Experimentally validated |
Pfam : |
PF08023 : Antimicrobial_2 ( Frog antimicrobial peptide )
|
InterPro : |
IPR012521 : Antimicrobial_frog_2.
|
AMP Family : |
Esculentin |
Gene Ontology : |
GO ID |
Ontology |
Definition |
Evidence |
GO:0005576 |
Cellular component |
Extracellular region |
IDA |
GO:0050829 |
Biological process |
Defense response to Gram-negative bacterium |
IDA |
GO:0050830 |
Biological process |
Defense response to Gram-positive bacterium |
IDA |
GO:0044179 |
Biological process |
Hemolysis in other organism |
IDA |
|
Length : |
46 |
Sequence: |
GIFSKLGRKKIKNLLISGLKNVGKEVGMDVVRTGIDIAGCKIKGEC |