CAMPSQ45
Title : Latarcin-3a
GenInfo Identifier : 115311723
Source : Lachesana tarabaevi [Spider]
Taxonomy : Animalia, Arachnida
UniProt: Q1ELU3
PubMed : 16735513
Activity : Antibacterial, Antifungal
Gram Nature : Gram +ve, Gram -ve
Target :
A. globiformis VKM Ac-1112 ( MIC = 0.3 microM ), B. subtilis VKM B-501 ( MIC = 1.2 microM ), E.coli DH5-alpha ( MIC = 2.5 microM ), E. coli MH1 ( MIC = 6.0 microM ), P.aeruginosa PAO1 ( MIC = >40 microM ), P. pastoris GS115 ( MIC = 20 microM ), S.cerevisiae Y190 ( MIC = 20 microM)
Hemolytic Activity :
Rabbit erythrocytes ( Hemolysis > 120 microM )
Validated : Experimentally validated
Pfam : PF10279 : Latarcin ( Latarcin precursor )
InterPro : IPR018802 : Latarcin_precursor.
AMP Family : Latarcin
Signature :
ID Type Pattern / HMM
LatarcinH20_2 HMM
LatarcinH_13 HMM
LatarcinP20_2 Pattern S-W-x-S-M-A-K-K-L-K-E-Y-M-E-K-L-K-Q-R-A
Gene Ontology :
GO ID Ontology Definition
Evidence
GO:0005576 Cellular component Extracellular region IEA
GO:0016020 Cellular component Membrane IEA
GO:0090729 Molecular function Toxin activity IEA
GO:0042742 Biological process Defense response to bacterium IEA
GO:0050832 Biological process Defense response to fungus IEA
GO:0031640 Biological process Killing of cells of other organism IEA
Length : 20
Sequence:
SWKSMAKKLKEYMEKLKQRA

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