| CAMPSQ43 |
| Title : |
Latarcin-2a |
| GenInfo Identifier : |
115311721 |
| Source : |
Lachesana tarabaevi [Spider] |
| Taxonomy : |
Animalia, Arachnida |
| UniProt: |
Q1ELU1 |
| PDB: |
2G9P |
| Structure Database : |
CAMPST125 |
| PubMed : |
16735513, 19563807 |
| Activity : |
Antibacterial, Antifungal |
| Gram Nature : |
Gram +ve, Gram -ve |
| Target : |
[Refer PubMed ID - 16735513: A. globiformis VKM Ac-1112 ( MIC = 0.7 microM ), B. subtilis VKM B-501 ( MIC = 0.4 microM ), E. coli DH5-alpha ( MIC = 1.0 microM ), E. coli MH1 ( MIC = 0.7 microM ), P. aeruginosa PAO1 ( MIC = 6.7 microM ), P. pastoris GS115 ( MIC = 6.7 microM ), S. cerevisiae Y190 ( MIC = 54 microM)], [Refer PubMed ID - 19563807: E. coli ( MIC = 3 microM ), B. subtilis ( MIC = 0.7 microM ), S. aureus ( MIC = 1.5 microM )] |
| Hemolytic Activity : |
Human erythrocytes (EC50 = 6microM) |
| Validated : |
Experimentally validated |
| Comment : |
Refer PubMed ID 19563807: C terminal: OH |
| Pfam : |
PF10279 : Latarcin ( Latarcin precursor )
|
| InterPro : |
IPR018802 : Latarcin_precursor.
|
| AMP Family : |
Latarcin |
| Signature : |
| ID |
Type |
Pattern / HMM |
|
LatarcinH26_2 |
HMM |
 |
|
LatarcinH_13 |
HMM |
|
|
LatarcinP26_2 |
Pattern |
G-L-F-G-K-L-I-K-K-F-G-R-K-A-I-S-Y-A-V-K-K-A-R-G-K |
|
| Gene Ontology : |
| GO ID |
Ontology |
Definition |
Evidence |
| GO:0005576 |
Cellular component |
Extracellular region |
IEA |
| GO:0090729 |
Molecular function |
Toxin activity |
IEA |
| GO:0042742 |
Biological process |
Defense response to bacterium |
IEA |
| GO:0050832 |
Biological process |
Defense response to fungus |
IEA |
| GO:0044179 |
Biological process |
Hemolysis in other organism |
IEA |
|
| Length : |
26 |
Sequence: |
GLFGKLIKKFGRKAISYAVKKARGKH |
