| CAMPSQ4150 |
| Title : |
Nigrocin-2JDa |
| GenInfo Identifier : |
410591646 |
| Source : |
Odorrana jingdongensis [Jingdong frog] |
| Taxonomy : |
Animalia, Amphibia |
| UniProt: |
B3A0M6 |
| PubMed : |
22917879 |
| Activity : |
Antibacterial, Antifungal |
| Gram Nature : |
Gram +ve, Gram -ve |
| Target : |
Staphylococcus aureus (ATCC 25923) ( MIC=32microg/ml ), Methicillin-resistant S. aureus (MRSA, CIB 85462) ( MIC=16microg/ml ), Escherichia coli (ATCC 25922) ( MIC=32microg/ml ), Extended-spectrum-lactamases E. coli (ESBL, CIB 84492) ( MIC=32microg/ml), Candida albicans ( MIC = 128microg/ml) |
| Hemolytic Activity : |
Rabbit erythrocytes 80.3±5.5% hemolysis (128microg/ml) |
| Validated : |
Experimentally validated |
| Pfam : |
PF16047: Antimicrobial22
|
| AMP Family : |
Nigrocin |
| Signature : |
| ID |
Type |
Pattern / HMM |
|
NigrocinH21_35 |
HMM |
 |
|
NigrocinH_39 |
HMM |
|
|
| Gene Ontology : |
| GO ID |
Ontology |
Definition |
Evidence |
| GO:0005576 |
Cellular component |
Extracellular region |
IEA |
| GO:0050832 |
Biological process |
Defense response to fungus |
IDA |
| GO:0050829 |
Biological process |
Defense response to Gram-negative bacterium |
IDA |
| GO:0050830 |
Biological process |
Defense response to Gram-positive bacterium |
IDA |
| GO:0044179 |
Biological process |
Hemolysis in other organism |
IDA |
|
| Length : |
21 |
Sequence: |
GIFGKILGAGKKVLCGLSGLC |
