CAMPSQ3886 |
Title : |
Histone H2B type 1-J |
Source : |
Homo sapiens [Human] |
Taxonomy : |
Animalia, Mammals |
UniProt: |
P06899 |
PubMed : |
11859126 |
Activity : |
Antibacterial |
Gram Nature : |
Gram -ve |
Target : |
Escherichia coli ( MIC = 10 microg/ml ) |
Validated : |
Experimentally validated |
Pfam : |
PF00125 : Histone ( Core histone H2A/H2B/H3/H4 )
|
InterPro : |
IPR009072 : Histone-fold.
IPR007125 : Histone_core_D.
IPR000558 : Histone_H2B.
|
Gene Ontology : |
GO ID |
Ontology |
Definition |
Evidence |
GO:0043505 |
Cellular component |
CENP-A containing nucleosome |
IPI |
GO:0005829 |
Cellular component |
Cytosol |
IDA |
GO:0005615 |
Cellular component |
Extracellular space |
IDA |
GO:0005654 |
Cellular component |
Nucleoplasm |
IDA |
GO:0000786 |
Cellular component |
Nucleosome |
IPI |
GO:0005634 |
Cellular component |
Nucleus |
IDA |
GO:0003677 |
Molecular function |
DNA binding |
IBA |
GO:0001530 |
Molecular function |
Lipopolysaccharide binding |
IDA |
GO:0046982 |
Molecular function |
Protein heterodimerization activity |
IEA |
GO:0019731 |
Biological process |
Antibacterial humoral response |
IDA |
GO:0061844 |
Biological process |
Antimicrobial humoral immune response mediated by antimicrobial peptide |
IDA |
GO:0050829 |
Biological process |
Defense response to Gram-negative bacterium |
IDA |
GO:0050830 |
Biological process |
Defense response to Gram-positive bacterium |
IDA |
GO:0002227 |
Biological process |
Innate immune response in mucosa |
IDA |
GO:0031640 |
Biological process |
Killing of cells of other organism |
IDA |
GO:0010804 |
Biological process |
Negative regulation of tumor necrosis factor-mediated signaling pathway |
IDA |
GO:0006334 |
Biological process |
Nucleosome assembly |
IBA |
|
Length : |
125 |
Sequence: |
PEPAKSAPAPKKGSKKAVTKAQKKDGKKRKRSRKESYSIYVYKVLKQVHPDTGISSKAMG IMNSFVNDIFERIAGEASRLAHYNKRSTITSREIQTAVRLLLPGELAKHAVSEGTKAVTK YTSAK |