| CAMPSQ3830 |
| Title : |
CCL27 |
| Source : |
Homo sapiens [Human] |
| Taxonomy : |
Animalia, Mammals |
| UniProt: |
Q9Y4X3 |
| PDB: |
2KUM |
| Structure Database : |
CAMPST631 |
| PubMed : |
12538707 |
| Activity : |
Antibacterial |
| Gram Nature : |
Gram +ve, Gram -ve |
| Target : |
Pseudomonas aeruginosa ( IC50 > 10 microM ), Klebsiella pneumoniae ( IC50 > 10 microM ), Streptococcus mutans ( IC50 > 10 microM ), Streptococcus pyogenes ( IC50 > 10 microM ), Staphylococcus aureus( IC50 > 10 microM ), Candida albicans( IC50 = 5.0+/- 1.9 microM ), C. albicans ( IC50 = 5.0+/- 1.9 microM) |
| Validated : |
Experimentally validated |
| Pfam : |
PF00048 : IL8 ( Small cytokines (intecrine/chemokine), interleukin-8 like )
|
| Gene Ontology : |
| GO ID |
Ontology |
Definition |
Evidence |
| GO:0005576 |
Cellular component |
Extracellular region |
IBA |
| GO:0005615 |
Cellular component |
Extracellular space |
IEA |
| GO:0031728 |
Molecular function |
CCR3 chemokine receptor binding |
IPI |
| GO:0008009 |
Molecular function |
Chemokine activity |
IBA |
| GO:0061844 |
Biological process |
Antimicrobial humoral immune response mediated by antimicrobial peptide |
IDA |
| GO:0007267 |
Biological process |
Cell-cell signaling |
TAS |
| GO:0006935 |
Biological process |
Chemotaxis |
TAS |
| GO:0006955 |
Biological process |
Immune response |
TAS |
| GO:0031640 |
Biological process |
Killing of cells of other organism |
IDA |
| GO:2000251 |
Biological process |
Positive regulation of actin cytoskeleton reorganization |
IBA |
| GO:0010820 |
Biological process |
Positive regulation of T cell chemotaxis |
IBA |
|
| Length : |
56 |
Sequence: |
PPSTACCTQLYRKPLSDKLLRKVIQVELQEADGDCHLQAFVLHLAQRSICIHPQNP |
