CAMPSQ3746
Title : CCL11
Source : Homo sapiens [Human]
Taxonomy : Animalia, Mammals
UniProt: P51671
PDB: 2EOT
Structure Database : CAMPST624
PubMed : 12949249
Activity : Antibacterial
Gram Nature : Gram +ve, Gram -ve
Target :
Escherichia coli ATCC25922, Staphylococcus aureus ATCC29213
Validated : Experimentally validated
Pfam : PF00048 : IL8 ( Small cytokines (intecrine/chemokine), interleukin-8 like )
Gene Ontology :
GO ID Ontology Definition
Evidence
GO:0005576 Cellular component Extracellular region IDA
GO:0005615 Cellular component Extracellular space IBA
GO:0048020 Molecular function CCR chemokine receptor binding IBA
GO:0031728 Molecular function CCR3 chemokine receptor binding IDA
GO:0008009 Molecular function Chemokine activity IDA
GO:0046983 Molecular function Protein dimerization activity IDA
GO:0048018 Molecular function Receptor ligand activity IDA
GO:0061844 Biological process Antimicrobial humoral immune response mediated by antimicrobial peptide IDA
GO:0060444 Biological process Branching involved in mammary gland duct morphogenesis IEA
GO:0007155 Biological process Cell adhesion TAS
GO:0006874 Biological process Cellular calcium ion homeostasis TAS
GO:0071346 Biological process Cellular response to interferon-gamma IBA
GO:0071347 Biological process Cellular response to interleukin-1 IBA
GO:0071356 Biological process Cellular response to tumor necrosis factor IBA
GO:0070098 Biological process Chemokine-mediated signaling pathway IBA
GO:0006935 Biological process Chemotaxis TAS
GO:0007010 Biological process Cytoskeleton organization IDA
GO:0048245 Biological process Eosinophil chemotaxis IDA
GO:0007186 Biological process G protein-coupled receptor signaling pathway IBA
GO:0006954 Biological process Inflammatory response IBA
GO:0031640 Biological process Killing of cells of other organism IDA
GO:0007611 Biological process Learning or memory ISS
GO:0048247 Biological process Lymphocyte chemotaxis IBA
GO:0060763 Biological process Mammary duct terminal end bud growth IEA
GO:0090647 Biological process Modulation of age-related behavioral decline ISS
GO:0002548 Biological process Monocyte chemotaxis IBA
GO:0050768 Biological process Negative regulation of neurogenesis ISS
GO:0030593 Biological process Neutrophil chemotaxis IBA
GO:0030838 Biological process Positive regulation of actin filament polymerization IDA
GO:0045766 Biological process Positive regulation of angiogenesis IEA
GO:0030335 Biological process Positive regulation of cell migration IDA
GO:0001938 Biological process Positive regulation of endothelial cell proliferation IDA
GO:0070374 Biological process Positive regulation of ERK1 and ERK2 cascade IBA
GO:0043547 Biological process Positive regulation of GTPase activity IDA
GO:0006468 Biological process Protein phosphorylation TAS
GO:0008360 Biological process Regulation of cell shape IDA
GO:0009314 Biological process Response to radiation TAS
GO:0009615 Biological process Response to virus TAS
GO:0007165 Biological process Signal transduction TAS
Length : 74
Sequence:
 GPASVPTTCCFNLANRKIPLQRLESYRRITSGKCPQKAVIFKTKLAKDICADPKKKWVQD
SMKYLDQKSPTPKP

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