CAMPSQ3735
Title : CXCL1
Source : Homo sapiens [Human]
Taxonomy : Animalia, Mammals
UniProt: P09341
PDB: 1MSH
Structure Database : CAMPST617
PubMed : 12949249
Activity : Antibacterial
Gram Nature : Gram +ve, Gram -ve
Target :
Escherichia coli ATCC25922, Staphylococcus aureus ATCC29213
Validated : Experimentally validated
Pfam : PF00048 : IL8 ( Small cytokines (intecrine/chemokine), interleukin-8 like )
InterPro : IPR001089 : Chemokine_CXC.
IPR001089 :
IPR018048 : Chemokine_CXC_CS.
IPR018048 :
IPR001811 : Chemokine_IL8-like_dom.
IPR001811 :
Gene Ontology :
GO ID Ontology Definition
Evidence
GO:0005576 Cellular component Extracellular region TAS
GO:0005615 Cellular component Extracellular space IBA
GO:0035580 Cellular component Specific granule lumen TAS
GO:1904724 Cellular component Tertiary granule lumen TAS
GO:0008009 Molecular function Chemokine activity IBA
GO:0045236 Molecular function CXCR chemokine receptor binding IBA
GO:0008047 Molecular function Enzyme activator activity TAS
GO:0008083 Molecular function Growth factor activity TAS
GO:0005102 Molecular function Signaling receptor binding TAS
GO:0030036 Biological process Actin cytoskeleton organization TAS
GO:0061844 Biological process Antimicrobial humoral immune response mediated by antimicrobial peptide IDA
GO:0071222 Biological process Cellular response to lipopolysaccharide IBA
GO:0070098 Biological process Chemokine-mediated signaling pathway IBA
GO:0006935 Biological process Chemotaxis TAS
GO:0007186 Biological process G protein-coupled receptor signaling pathway TAS
GO:0006954 Biological process Inflammatory response IBA
GO:0035556 Biological process Intracellular signal transduction TAS
GO:0031640 Biological process Killing of cells of other organism IDA
GO:0008285 Biological process Negative regulation of cell population proliferation TAS
GO:0007399 Biological process Nervous system development TAS
GO:0030593 Biological process Neutrophil chemotaxis IBA
GO:0007165 Biological process Signal transduction TAS
Length : 73
Sequence:
 ASVATELRCQCLQTLQGIHPKNIQSVNVKSPGPHCAQTEVIATLKNGRKACLNPASPIVK
KIIEKMLNSDKSN

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