CAMPSQ3734
Title : CCL20
Source : Homo sapiens [Human]
Taxonomy : Animalia, Mammals
UniProt: P78556
PDB: 1M8A
Structure Database : CAMPST616
PubMed : 12949249
Activity : Antibacterial
Gram Nature : Gram +ve, Gram -ve
Target :
Escherichia coli ATCC25922, Staphylococcus aureus ATCC29213
Validated : Experimentally validated
Pfam : PF00048 : IL8 ( Small cytokines (intecrine/chemokine), interleukin-8 like )
Gene Ontology :
GO ID Ontology Definition
Evidence
GO:0005576 Cellular component Extracellular region TAS
GO:0005615 Cellular component Extracellular space IBA
GO:0048020 Molecular function CCR chemokine receptor binding IBA
GO:0031731 Molecular function CCR6 chemokine receptor binding IDA
GO:0008009 Molecular function Chemokine activity IBA
GO:0061844 Biological process Antimicrobial humoral immune response mediated by antimicrobial peptide IDA
GO:0035584 Biological process Calcium-mediated signaling using intracellular calcium source IDA
GO:0060326 Biological process Cell chemotaxis IDA
GO:0007267 Biological process Cell-cell signaling TAS
GO:0071346 Biological process Cellular response to interferon-gamma IBA
GO:0071347 Biological process Cellular response to interleukin-1 IBA
GO:0071356 Biological process Cellular response to tumor necrosis factor IBA
GO:0070098 Biological process Chemokine-mediated signaling pathway IBA
GO:0006935 Biological process Chemotaxis IDA
GO:0042742 Biological process Defense response to bacterium IEA
GO:0007186 Biological process G protein-coupled receptor signaling pathway IBA
GO:0006955 Biological process Immune response TAS
GO:0006954 Biological process Inflammatory response IBA
GO:0031640 Biological process Killing of cells of other organism IDA
GO:0048247 Biological process Lymphocyte chemotaxis IBA
GO:0002548 Biological process Monocyte chemotaxis IBA
GO:0030593 Biological process Neutrophil chemotaxis IBA
GO:0070374 Biological process Positive regulation of ERK1 and ERK2 cascade IBA
GO:0043547 Biological process Positive regulation of GTPase activity IBA
GO:2000406 Biological process Positive regulation of T cell migration IDA
GO:0007165 Biological process Signal transduction TAS
GO:0072678 Biological process T cell migration ISS
GO:0072679 Biological process Thymocyte migration ISS
Length : 69
Sequence:
 SNFDCCLGYTDRILHPKFIVGFTRQLANEGCDINAIIFHTKKKLSVCANPKQTWVKYIVR
LLSKKVKNM

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