CAMPSQ3730 |
Title : |
RegIIIalpha |
Source : |
Homo sapiens [Human] |
Taxonomy : |
Animalia, Mammals |
UniProt: |
Q06141 |
PDB: |
2GO0 |
Structure Database : |
CAMPST614 |
PubMed : |
16931762 |
Activity : |
Antibacterial |
Gram Nature : |
Gram +ve, Gram -ve |
Target : |
Listeria monocytogenes, Listeria innocua, Enterococcus faecalis, Escherichia coli |
Validated : |
Experimentally validated |
Pfam : |
PF00059 : Lectin_C ( Lectin C-type domain )
|
Gene Ontology : |
GO ID |
Ontology |
Definition |
Evidence |
GO:0005737 |
Cellular component |
Cytoplasm |
TAS |
GO:0005576 |
Cellular component |
Extracellular region |
TAS |
GO:0005615 |
Cellular component |
Extracellular space |
IBA |
GO:0030246 |
Molecular function |
Carbohydrate binding |
TAS |
GO:0042802 |
Molecular function |
Identical protein binding |
IPI |
GO:0070492 |
Molecular function |
Oligosaccharide binding |
IBA |
GO:0042834 |
Molecular function |
Peptidoglycan binding |
IBA |
GO:0038023 |
Molecular function |
Signaling receptor activity |
IBA |
GO:0006953 |
Biological process |
Acute-phase response |
IEA |
GO:0061844 |
Biological process |
Antimicrobial humoral immune response mediated by antimicrobial peptide |
IBA |
GO:0044278 |
Biological process |
Cell wall disruption in other organism |
IBA |
GO:0007157 |
Biological process |
Heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules |
TAS |
GO:0045617 |
Biological process |
Negative regulation of keratinocyte differentiation |
ISS |
GO:0008284 |
Biological process |
Positive regulation of cell population proliferation |
IBA |
GO:0010838 |
Biological process |
Positive regulation of keratinocyte proliferation |
ISS |
GO:0090303 |
Biological process |
Positive regulation of wound healing |
ISS |
GO:0043434 |
Biological process |
Response to peptide hormone |
IBA |
|
Length : |
149 |
Sequence: |
EEPQRELPSARIRCPKGSKAYGSHCYALFLSPKSWTDADLACQKRPSGNLVSVLSGAEGS FVSSLVKSIGNSYSYVWIGLHDPTQGTEPNGEGWEWSSSDVMNYFAWERNPSTISSPGHC ASLSRSTAFLRWKDYNCNVRLPYVCKFTD |