CAMPSQ3316 |
Title : |
Cathelicidin, EA-CATH1 |
GenInfo Identifier : |
225579557 |
Source : |
Equus asinus [Donkey] |
Taxonomy : |
Animalia, Mammals |
UniProt: |
C1K8V9 |
PubMed : |
20423460 |
Activity : |
Antibacterial |
Gram Nature : |
Gram -ve |
Target : |
Staphylococcus aureus (IS) (MIC = 1.2 microg/ml), Staphylococcus aureus ATCC2592 (MIC = 0.6 microg/ml), Staphylococcus haemolyticus (092401) (IS, DRa) (MIC = 0.6 microg/ml), Nocardia asteroids (IS) (MIC = 1.2 microg/ml), Enterococcus faecium (IS091299) (MIC = 9.4 microg/ml), Propionibacterium acnes ATCC11827 (MIC = 4.7 microg/ml), Klebsiella oxytoca (IS) (MIC = > 100 microg/ml), Aeromonas sobria (IS) (MIC = 9.4 microg/ml), Acinetobacter baumannii 092178 (IS, DRb) (MIC = 4.7 microg/ml), Acinetobacter baumannii 092373 (IS) (MIC = 9.4 microg/ml), Stenotrophomonas maltophilia (IS) (MIC = 9.4 microg/ml), Pseudomonas aeruginosa ATCC27853 (MIC = > 100 microg/ml), Pseudomonas aeruginosa 091411(IS) (MIC = 18.8 microg/ml), Pseudomonas aeruginosa 091412 (IS) (MIC = > 100 microg/ml), Pseudomonas aeruginosa 091413 (IS) (MIC = > 100 microg/ml), Escherichia coli 091335 (IS) (MIC = 75 microg/ml), Klebsiella pneumoniae 091372 (IS) (MIC = > 100 microg/ml), Klebsiella pneumoniae 091373 (IS) (MIC = > 100 microg/ml), Proteus vulgaris (IS) (MIC = > 100 microg/ml), Proteus mirabilis (IS) (MIC = > 100 microg/ml), Candida albicans 092251 (IS) (MIC = 9.4 microg/ml), Candida albicans ATCC2002 (MIC = 9.4 microg/ml), Slime mould (MIC = 4.7 microg/ml), Candida glabrata 090902 (IS) (MIC = > 100 microg/ml), Candida tropicalis 092422 (IS) (MIC = > 100 microg/ml), |
Validated : |
Experimentally validated |
Comment : |
These organisms did not show activity at a dose of 2mg/ml: Escherichia coli ATCC25922, Escherichia coli 090223 (IS), Serratia marcescens 091379 (IS), Klebsiella pneumoniae 091400 (IS), Salmonella typhi 091408 (IS), Cryptococcus neoformans (IS) |
AMP Family : |
Cathelicidin |
Signature : |
ID |
Type |
Pattern / HMM |
CathelicidinH25_3 |
HMM |
|
CathelicidinH_140 |
HMM |
|
|
Gene Ontology : |
GO ID |
Ontology |
Definition |
Evidence |
GO:0005576 |
Cellular component |
Extracellular region |
IEA |
GO:0006952 |
Biological process |
Defense response |
IEA |
GO:0006955 |
Biological process |
Immune response |
IEA |
GO:0051707 |
Biological process |
Response to other organism |
IEA |
|
Length : |
25 |
Sequence: |
KRRGSVTTRYQFLMIHLLRPKKLFA |