| CAMPSQ3084 |
| Title : |
Human granulysin |
| Source : |
Homo sapiens [Human] |
| Taxonomy : |
Animalia, Mammals |
| UniProt: |
P22749 |
| PDB: |
1L9L |
| Structure Database : |
CAMPST638 |
| PubMed : |
9756476 |
| Activity : |
Antibacterial, Antifungal |
| Gram Nature : |
Gram +ve, Gram -ve |
| Target : |
Salmonella typhimurium, Listeria monocytogenes, Escherichia coli, Staphylococcus aureus, Cryptococcus neoformans, Candida albicans, Leishmania major , Mycobacterium tuberculosis |
| Validated : |
Experimentally validated |
| InterPro : |
IPR008138 : SapB_2.
IPR011001 : Saposin-like.
IPR008139 : SaposinB.
|
| Gene Ontology : |
| GO ID |
Ontology |
Definition |
Evidence |
| GO:0005576 |
Cellular component |
Extracellular region |
TAS |
| GO:0005615 |
Cellular component |
Extracellular space |
TAS |
| GO:0097013 |
Cellular component |
Phagocytic vesicle lumen |
TAS |
| GO:0061844 |
Biological process |
Antimicrobial humoral immune response mediated by antimicrobial peptide |
IDA |
| GO:0006968 |
Biological process |
Cellular defense response |
IDA |
| GO:0042742 |
Biological process |
Defense response to bacterium |
IDA |
| GO:0050832 |
Biological process |
Defense response to fungus |
IEA |
| GO:0031640 |
Biological process |
Killing of cells of other organism |
IDA |
| GO:0005576 |
Cellular component |
Extracellular region |
TAS |
| GO:0005615 |
Cellular component |
Extracellular space |
TAS |
| GO:0097013 |
Cellular component |
Phagocytic vesicle lumen |
TAS |
| GO:0061844 |
Biological process |
Antimicrobial humoral immune response mediated by antimicrobial peptide |
IDA |
| GO:0006968 |
Biological process |
Cellular defense response |
IDA |
| GO:0042742 |
Biological process |
Defense response to bacterium |
IDA |
| GO:0050832 |
Biological process |
Defense response to fungus |
IEA |
| GO:0031640 |
Biological process |
Killing of cells of another organism |
IDA |
|
| Length : |
83 |
Sequence: |
GRDYRTCLTIVQKLKKMVDKPTQRSVSNAATRVCRTGRSRWRDVCRNFMRRYQSRVTQGL
VAGETAQQICEDLRLCIPSTGPL |
