| CAMPSQ228 |
| Title : |
Aurein-1.2 |
| GenInfo Identifier : |
20137307 |
| Source : |
Litoria raniformis [Southern bell frog] |
| Taxonomy : |
Animalia, Amphibia |
| UniProt: |
P82387 |
| PDB: |
1VM5 |
| Structure Database : |
CAMPST553 |
| PubMed : |
10951191, 15572363, 30593676, 30630076, 30043322 |
| Activity : |
Antibacterial, Anticancer |
| Gram Nature : |
Gram +ve, Gram -ve |
| Target : |
[ Refer PubMed 10951191 : - B.cereus ( MIC = 100 microg/ml), L.lactis ( MIC = 12 microg/ml), L.innocua ( MIC = 100 microg/ml), M.luteus ( MIC = 100 microg/ml), P.multocida ( MIC = 100 microg/ml), S.aureus ( MIC = 50 microg/ml), S.epidermidis ( MIC = 50 microg/ml), S.uberis ( MIC = 50 microg/ml) ] [ Refer 15572363 :- E.coli ( MIC = 75 microM) ] [Refer 30593676 Bacillus subtilis ATCC 6051 ( MIC= 128 +/- 0.43 microg/ml), Staphylococcus aureus ATCC 25923 ( MIC=32 +/- 0.43 microg/ml), Escherichia coli ATCC 25922 ( MIC= 1.024 +/- 13.85 microg/ml), Pseudomonas aeruginosa ATCC 27853 ( MIC= 1.024 +/- 13.85 microg/ml)]; [Refer PubMed ID - 30630076: Mycobacterium tuberculosis (H37Rv) (MIC50= 43.9 +/- 4.7 microM)]; [Refer PubMed ID - 30043322: A. baumannii ATCC 19606 (MIC =16microg/ml)] |
| Validated : |
Experimentally validated |
| Pfam : |
PF08256 : Antimicrobial20 ( Aurein-like antibiotic peptide )
|
| InterPro : |
IPR013157 : Aurein_antimicrobial_peptide.
|
| AMP Family : |
Aurein |
| Signature : |
| ID |
Type |
Pattern / HMM |
|
AureinH13_4 |
HMM |
 |
|
AureinH_21 |
HMM |
|
|
AureinP13_4 |
Pattern |
G-L-F-D-I-I-K-x-I-x-[ES]-[GST]-[FIL] |
|
| Gene Ontology : |
| GO ID |
Ontology |
Definition |
Evidence |
| GO:0005576 |
Cellular component |
Extracellular region |
IEA |
| GO:0042742 |
Biological process |
Defense response to bacterium |
IEA |
| GO:0005576 |
Cellular component |
Extracellular region |
IEA |
| GO:0042742 |
Biological process |
Defense response to bacterium |
IEA |
|
| Length : |
13 |
Sequence: |
GLFDIIKKIAESF |
